# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2209430 | F | Inhibition of Ascaris induced early phase airway bronchoconstriction in sheep model at 1 mg/kg, iv qd for 7 days prior challenge | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
2. | ALA2209431 | F | Inhibition of Ascaris induced late phase airway bronchoconstriction in sheep model at 1 mg/kg, iv qd for 7 days prior challenge | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
3. | ALA2209432 | F | Inhibition of airway hyperresponsiveness in sheep model at 1 mg/kg, iv qd for 7 days prior challenge | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
4. | ALA2209433 | F | Inhibition of Ascaris-induced BAL fluid eosinophilia in sheep at 1 mg/kg, iv qd for 7 days | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
5. | ALA2209434 | F | Reversal of allergen-induced mucociliary clearance in sheep assessed as tracheal mucus velocity at 3 mg/kg, iv administered 24 hrs post challenge measured at 4 hrs relative to basal level | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
6. | ALA2209435 | F | Reversal of allergen-induced mucociliary clearance in sheep assessed as tracheal mucus velocity at 3 mg/kg, iv administered 24 hrs post challenge measured at 8 hrs relative to basal level | Ovis aries | 1 | ALA2203126 | organism-based format | Scientific Literature | |
7. | ALA2209436 | F | Antagonist activity at TXA2 receptor by FRET assay | 1 | ALA2203126 | assay format | Scientific Literature | ||
8. | ALA2209437 | A | Permeability in human Caco2 cells at pH 6 | Homo sapiens | 1 | ALA2203126 | cell-based format | Scientific Literature | |
9. | ALA2209438 | A | Inhibition of CYP3A4 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
10. | ALA2209439 | A | Inhibition of CYP2D6 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
11. | ALA2209440 | A | Inhibition of CYP2C9 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
12. | ALA2209441 | A | Inhibition of CYP2C19 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
13. | ALA2209442 | A | Inhibition of CYP2C8 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
14. | ALA2209443 | A | Inhibition of CYP2B6 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
15. | ALA2209444 | A | Inhibition of CYP1A2 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
16. | ALA2209445 | A | Inhibition of CYP2A6 | 1 | ALA2203126 | single protein format | Scientific Literature | ||
17. | ALA2209446 | T | Genotoxicity in Salmonella typhimurium by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2203126 | organism-based format | Scientific Literature | |
18. | ALA2209447 | B | Inhibition of human ERG channel at 33 uM | Homo sapiens | 1 | ALA2203126 | single protein format | Scientific Literature | |
19. | ALA2209448 | B | Selectivity ratio of IC50 for TP receptor expressed in NK-92 cells to IC50 for recombinant human CRTH2 receptor expressed in CHO-K1 cells | Homo sapiens | 1 | ALA2203126 | cell-based format | Scientific Literature | |
20. | ALA2209449 | B | Inhibition of mouse CRTH2 receptor | Mus musculus | 1 | ALA2203126 | single protein format | Scientific Literature |