# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2216149 | P | Aqueous solubility of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA2216150 | A | Permeability of the compound at pH 6.2 by PAMPA assay | 3 | assay format | Scientific Literature | |||
3. | ALA2216151 | B | Selectivity ratio of IC50 for human PI3Kalpha to IC50 for human PI3Kgamma | Homo sapiens | 7 | assay format | Scientific Literature | ||
4. | ALA2216152 | B | Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting | Homo sapiens | 20 | single protein format | Scientific Literature | ||
5. | ALA2216154 | B | Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting | Homo sapiens | 20 | single protein format | Scientific Literature | ||
6. | ALA2216155 | B | Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-induction measured after 5 mins by immunostaining method | Mus musculus | 20 | cell-based format | Scientific Literature |