# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2216149 | P | Aqueous solubility of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA2216150 | A | Permeability of the compound at pH 6.2 by PAMPA assay | 3 | assay format | Scientific Literature | |||
3. | ALA2216151 | B | Selectivity ratio of IC50 for human PI3Kalpha to IC50 for human PI3Kgamma | Homo sapiens | 7 | assay format | Scientific Literature | ||
4. | ALA2216152 | B | Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting | Homo sapiens | 20 | single protein format | Scientific Literature | ||
5. | ALA2216154 | B | Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting | Homo sapiens | 20 | single protein format | Scientific Literature | ||
6. | ALA2216155 | B | Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-induction measured after 5 mins by immunostaining method | Mus musculus | 20 | cell-based format | Scientific Literature | ||
7. | ALA3097331 | B | Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP | Homo sapiens | 17 | single protein format | Scientific Literature | ||
8. | ALA3097332 | T | Mutagenicity in Escherichia coli WP2uvrA up to 5000 ug/ml by Ames test in absence of rat S9 fraction | Escherichia coli | 6 | organism-based format | Scientific Literature | ||
9. | ALA3097333 | T | Mutagenicity in Escherichia coli WP2uvrA up to 5000 ug/ml by Ames test in presence of rat S9 fraction | Escherichia coli | 6 | organism-based format | Scientific Literature | ||
10. | ALA3097334 | T | Mutagenicity in Salmonella typhimurium TA100 up to 5000 ug/ml by Ames test in absence of rat S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 6 | organism-based format | Scientific Literature | ||
11. | ALA3097336 | T | Mutagenicity in Salmonella typhimurium TA98 up to 5000 ug/ml by Ames test in absence of rat S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 6 | organism-based format | Scientific Literature | ||
12. | ALA3097337 | T | Mutagenicity in Salmonella typhimurium TA98 up to 5000 ug/ml by Ames test in presence of rat S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 6 | organism-based format | Scientific Literature | ||
13. | ALA3097339 | T | Mutagenicity in Salmonella typhimurium TA100 up to 5000 ug/ml by Ames test in presence of rat S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 6 | organism-based format | Scientific Literature |