| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2209292 | B | Inhibition of MyD88 recruitment to TLR9 in C57BL/6 mouse BMDM cells assessed as inhibition of CpG-induced p38 MAPK activity up to 90 mins | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 2. | ALA2209293 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced p38 MAPK activity up to 90 mins | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 3. | ALA2209294 | B | Inhibition of MyD88 recruitment to IL-1R in C57BL/6 mouse BMDM cells assessed as inhibition of IL1-induced p38 MAPK activity up to 90 mins | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 4. | ALA2209295 | B | Inhibition of MyD88 recruitment to TLR4 cytoplasmic domain expressed in CHO cells at 25 to 50 uM incubated for 30 mins prior to CCf2/AM loading measured after 1 hr by beta-lactamase complementation assay | 1 | ALA2203171 | cell-based format | Scientific Literature | ||
| 5. | ALA2209296 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha degradation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 6. | ALA2209297 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 7. | ALA2209298 | B | Inhibition of MyD88 recruitment to TLR9 in C57BL/6 mouse BMDM cells assessed as inhibition of CpG-induced IkappaBalpha degradation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 8. | ALA2209299 | B | Inhibition of MyD88 recruitment to TLR9 in C57BL/6 mouse BMDM cells assessed as inhibition of CpG-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 9. | ALA2209300 | B | Inhibition of MyD88 recruitment to TLR2 in C57BL/6 mouse BMDM cells assessed as inhibition of HKSA-induced IkappaBalpha degradation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 10. | ALA2209301 | B | Inhibition of MyD88 recruitment to TLR2 in C57BL/6 mouse BMDM cells assessed as inhibition of HKSA-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 11. | ALA2209302 | B | Inhibition of MyD88 recruitment to IL-1R in C57BL/6 mouse BMDM cells assessed as inhibition of IL-1-induced IkappaBalpha degradation up to 90 mins by Western blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 12. | ALA2209718 | B | Inhibition of MyD88 recruitment to IL-1R in C57BL/6 mouse BMDM cells assessed as inhibition of IL-1-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 13. | ALA2209719 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced MCP1 phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 14. | ALA2209720 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 15. | ALA2209721 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced MCP1 phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 16. | ALA2209722 | B | Inhibition of IKKebta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
| 17. | ALA2209723 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced RelA phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 18. | ALA2209724 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 19. | ALA2209725 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
| 20. | ALA2209726 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced RelA phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature |
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