| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2211429 | F | Ratio of IC50 for human A2780 cells to IC50 for MMR-deficient human A2780/CP70 cells in presence of 10 uM MGMT inactivator Patrin2 | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA2211433 | P | Prodrug conversion in citrate-phosphate buffer at pH 8 assessed as pseudo-first-order rate constant | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA2211891 | P | Prodrug conversion in citrate-phosphate buffer at pH 7.4 assessed as pseudo-first-order rate constant | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA2211892 | P | Prodrug conversion in citrate-phosphate buffer at pH 4 assessed as pseudo-first-order rate constant | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA2211893 | F | Cytotoxicity against human U251 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA2211894 | P | Prodrug conversion in citrate-phosphate buffer at pH 8 assessed as half life of compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA2211895 | P | Prodrug conversion in citrate-phosphate buffer at pH 7.4 assessed as half life of compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA2211896 | F | Cytotoxicity against human A549 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA2211897 | P | Prodrug conversion in citrate-phosphate buffer at pH 4 assessed as half life of compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA2211898 | F | Cytotoxicity against human HCT116 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA2211899 | F | Cytotoxicity against human PANC1 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA2211900 | F | Cytotoxicity against human HT-29 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA2211901 | F | Cytotoxicity against human DLD1 cells after 5 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA2211902 | F | Cytotoxicity against MMR-deficient human A2780/CP70 cells after 5 days by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA2211903 | F | Cytotoxicity against MMR-deficient human A2780/CP70 cells after 5 days by MTT assay in presence of 10 uM MGMT inactivator Patrin2 | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA2211904 | F | Cytotoxicity against human A2780 cells after 5 days by MTT assay in presence of 10 uM MGMT inactivator Patrin2 | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA2211905 | F | Cytotoxicity against human A2780 cells after 5 days by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA2211906 | B | Binding affinity to Escherichia coli pBR322 DNA assessed as guanine-N7 alkylation on GC-rich region after 2 hrs by piperidine cleavage assay | Escherichia coli | 3 | nucleic acid format | Scientific Literature | ||
| 19. | ALA2211907 | B | Induction of Escherichia coli pBR322 DNA alkylation assessed as formation of covalent DNA adducts after 2 hrs by Taq polymerase DNA stop assay | Escherichia coli | 3 | nucleic acid format | Scientific Literature | ||
| 20. | ALA2423974 | F | Ratio of IC50 for human HCT116 cells expressing p53 to IC50 for p53-deficient human HCT116 cells | Homo sapiens | 7 | cell-based format | Scientific Literature |
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