# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2215893 | B | Inhibition of PI3Kgamma by kinobeads assay | 14 | ALA2203257 | single protein format | Scientific Literature | ||
2. | ALA2215894 | B | Inhibition of PI3Kalpha assessed as change in pIC50 by kinobeads assay | 14 | ALA2203257 | single protein format | Scientific Literature | ||
3. | ALA2215895 | B | Inhibition of PI3Kbeta assessed as change in pIC50 by kinobeads assay | 14 | ALA2203257 | single protein format | Scientific Literature | ||
4. | ALA2215896 | B | Inhibition of PI3Kdelta assessed as change in pIC50 by kinobeads assay | 14 | ALA2203257 | single protein format | Scientific Literature | ||
5. | ALA2215897 | B | Inhibition of PI3Kgamma/delta by neutrophil migration assay | 11 | ALA2203257 | protein format | Scientific Literature | ||
6. | ALA2216331 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 2 | ALA2203257 | microsome format | Scientific Literature | |
7. | ALA2216333 | A | Oral bioavailability in rat liver microsomes at 5 mg/kg; 1 mg/kg, iv | Rattus norvegicus | 1 | ALA2203257 | organism-based format | Scientific Literature | |
8. | ALA2216335 | A | Volume of distribution at steady state in rat liver microsomes at 5 mg/kg, po; 1 mg/kg, iv | Rattus norvegicus | 1 | ALA2203257 | organism-based format | Scientific Literature | |
9. | ALA2216337 | A | Half life in rat liver microsomes at 5 mg/kg, po; 1 mg/kg, iv | Rattus norvegicus | 1 | ALA2203257 | organism-based format | Scientific Literature | |
10. | ALA2216339 | A | Cmax in rat liver microsomes at 5 mg/kg, po; 1 mg/kg, iv | Rattus norvegicus | 1 | ALA2203257 | organism-based format | Scientific Literature | |
11. | ALA2216341 | A | AUC in rat liver microsomes at 5 mg/kg, po; 1 mg/kg, iv | Rattus norvegicus | 1 | ALA2203257 | organism-based format | Scientific Literature | |
12. | ALA2216342 | A | Clearance in cynomolgus monkey | Macaca fascicularis | 1 | ALA2203257 | organism-based format | Scientific Literature | |
13. | ALA2216343 | A | Half life in cynomolgus monkey | Macaca fascicularis | 1 | ALA2203257 | organism-based format | Scientific Literature | |
14. | ALA2216344 | A | Oral bioavailability in cynomolgus monkey | Macaca fascicularis | 1 | ALA2203257 | organism-based format | Scientific Literature | |
15. | ALA2216345 | B | Inhibition of human ERG at >250 uM by patch clamp method | Homo sapiens | 1 | ALA2203257 | assay format | Scientific Literature | |
16. | ALA2216346 | A | Inhibition of CYP1A2 at >20 uM | 1 | ALA2203257 | single protein format | Scientific Literature | ||
17. | ALA2216347 | A | Inhibition of CYP2D6 at >20 uM | 1 | ALA2203257 | single protein format | Scientific Literature | ||
18. | ALA2216348 | A | Inhibition of CYP2C9 at >20 uM | 1 | ALA2203257 | single protein format | Scientific Literature | ||
19. | ALA2216349 | A | Inhibition of CYP2C19 at >20 uM | 1 | ALA2203257 | single protein format | Scientific Literature | ||
20. | ALA2216350 | A | Inhibition of CYP3A4 at >20 uM | 1 | ALA2203257 | single protein format | Scientific Literature |