# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2215078 | Binding | Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs relative to basal level | Homo sapiens | 15 | ALA2203007 | cell-based format | Scientific Literature | |
2. | ALA2215079 | Binding | Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
3. | ALA2215080 | Binding | Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs relative to basal level | Homo sapiens | 11 | ALA2203007 | cell-based format | Scientific Literature | |
4. | ALA2215081 | Binding | Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
5. | ALA2215082 | Functional | Allosteric modulation at human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis relative to basal level | Homo sapiens | 17 | ALA2203007 | cell-based format | Scientific Literature | |
6. | ALA2215084 | Functional | Ratio of ZnBip EC50 to compound EC50 for human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 6 | ALA2203007 | cell-based format | Scientific Literature | |
7. | ALA2215085 | Physicochemical | Binding affinity to Zn(II) after 2 hrs using FluoZin-3 by fuorescence assay | 22 | ALA2203007 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA2215086 | Functional | Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
9. | ALA2215087 | Functional | Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
10. | ALA2215088 | Functional | Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | ALA2203007 | cell-based format | Scientific Literature | |
11. | ALA2215089 | Functional | Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis relative to basal level | Homo sapiens | 20 | ALA2203007 | cell-based format | Scientific Literature | |
12. | ALA2215090 | Functional | Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis relative to basal level | Homo sapiens | 13 | ALA2203007 | cell-based format | Scientific Literature | |
13. | ALA2215091 | Functional | Ratio of ZnBip EC50 to compound EC50 for human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 6 | ALA2203007 | cell-based format | Scientific Literature | |
14. | ALA2215093 | Functional | Ratio of ZnBip EC50 to compound EC50 for human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 4 | ALA2203007 | cell-based format | Scientific Literature | |
15. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
16. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
17. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
18. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
19. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
20. | ALA4808151 | Binding | Hit confirmation of the active molecules of the enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 249 | ALA4808148 | single protein format | Fraunhofer HDAC6 |