# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2214906 | F | Agonist activity at TrkB receptor in E17 rat embryo primary neurons assessed as Akt phosphorylation at serine 473 at 500 nM after 15 mins by immunoblotting analysis | Rattus norvegicus | 11 | ALA2203249 | assay format | Scientific Literature | |
2. | ALA2214907 | F | Agonist activity at TrkB receptor in E17 rat embryo primary neurons assessed as TrkB phosphorylation at tyrosine 817 at 500 nM after 15 mins by immunoblotting analysis | Rattus norvegicus | 11 | ALA2203249 | assay format | Scientific Literature | |
3. | ALA3861416 | F | Neuroprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr measured after 17 hrs by MTT assay relative to control | Homo sapiens | 20 | ALA3860078 | cell-based format | Scientific Literature | |
4. | ALA3861418 | T | Neurotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 3 to 10 uM after 24 hrs by MTT assay | Homo sapiens | 7 | ALA3860078 | cell-based format | Scientific Literature | |
5. | ALA3861430 | F | Neuroprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as increase in cell viability at 0.1 to 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr measured after 17 hrs by MTT assay relative to control | Homo sapiens | 6 | ALA3860078 | cell-based format | Scientific Literature |