# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2214930 | A | Drug metabolism in mouse plasma assessed as release of PTL | Mus musculus | 1 | cell-free format | Scientific Literature | ||
2. | ALA2209717 | F | Antitumor activity against mixed-lineage human leukemia cells xenografted in NOD/SCID mouse assessed as inhibition of cancer cell engrafting at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 35 | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
3. | ALA2210124 | F | Antitumor activity against mixed-lineage human leukemia cells xenografted in NOD/SCID mouse assessed as reduction of CD45+CD33+ cells in bone marrow at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 35 (Rvb = 9.8 %) | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
4. | ALA2210125 | F | Antitumor activity against human leukemia stem/progenitor cells xenografted in NOD/SCID mouse assessed as reduction of CD45+CD33+ cells in bone marrow at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 85 | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
5. | ALA2210126 | F | Antitumor activity against human leukemia stem/progenitor cells xenografted in NOD/SCID mouse assessed as survival rate at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 85 | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
6. | ALA2210129 | F | Antitumor activity against human leukemia stem/progenitor cells xenografted in NOD/SCID mouse assessed as survival time at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting (Rvb = 43 days) | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
7. | ALA2210146 | P | Drug degradation in HEPES buffer at pH 7.4 assessed as release of PTL up to 2.5 hrs | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA2210148 | P | Drug degradation in HEPES buffer at pH 7.4 assessed as release of PTL | 1 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA2210151 | P | Drug degradation in HEPES buffer at pH <5 assessed as release of PTL | 1 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA3119965 | F | Antiproliferative activity against human BxPC3 cells assessed as cell growth at 10 uM after 72 hrs by CellTitre assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
11. | ALA3119966 | F | Antiproliferative activity against human MIAPaCa2 cells assessed as cell growth at 10 uM after 72 hrs by CellTitre assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
12. | ALA3119967 | F | Antiproliferative activity against human PANC1 cells assessed as cell growth at 10 uM after 72 hrs by CellTitre assay relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
13. | ALA3240487 | F | Modulation of G2-M cell cycle progression in Xenopus oocytes assessed as effect on phenotype upon progression to GVBD during oocyte maturation in presence of progesterone | Xenopus | 11 | cell-based format | Scientific Literature |