| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2211878 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as decrease in retroperitoneal fat (Rvb = 1.41 +/- 0.29 %) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA2211879 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as decrease in abdominal and epididymal fat (Rvb = 5.34 +/- 1.09 %) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA2211880 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as decrease in total fat (Rvb = 6.75 +/- 1.18 %) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA2211881 | F | Antidyslipidemic activity in high fat diet-induced obese mouse assessed as increase in blood HDL-cholesterol level (Rvb = 17.4 +/- 2.15 mg/dl) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA2211887 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as inhibition of body weight gain at 10 mg/kg after 5 weeks (Rvb = 52.9 +/- 1.20 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2211888 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as inhibition of body weight gain at 10 mg/kg after 4 weeks (Rvb = 49.9 +/- 1.24 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2211889 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as inhibition of body weight gain at 10 mg/kg after 3 weeks (Rvb = 45.9 +/- 2.29 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2211890 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as inhibition of body weight gain at 10 mg/kg after 2 weeks (Rvb = 37.8 +/- 3.55 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2212360 | F | Antiobesity activity in high fat diet-induced obese mouse assessed as inhibition of body weight gain at 10 mg/kg after 1 week (Rvb = 35.2 +/- 1.57 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2212361 | A | Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2212362 | B | Inhibition of DGAT in human HepG2 cells using [14C]glycerol as substrate assessed as formation of [14C]-triglyceride at 10 uM by chromatographic analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2212886 | B | Inhibition of DGAT in human HepG2 cells using [14C]glycerol as substrate assessed as formation of [14C]-triglyceride at 3 uM by chromatographic analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2212887 | B | Inhibition of DGAT in human HepG2 cells using [14C]acetate as substrate assessed as formation of [14C]-triglyceride at 10 uM by chromatographic analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2212888 | B | Inhibition of DGAT in human HepG2 cells using [14C]acetate as substrate assessed as formation of [14C]-triglyceride at 3 uM by chromatographic analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2212889 | B | Inhibition of DGAT in rat liver microsomes | Rattus norvegicus | 23 | microsome format | Scientific Literature | ||
| 16. | ALA2212890 | F | Antidyslipidemic activity in high fat diet-induced obese mouse assessed as decrease in blood LDL-cholesterol level (Rvb = 119 +/- 14.3 mg/dl) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA2212891 | F | Antidyslipidemic activity in high fat diet-induced obese mouse assessed as decrease in total blood triglyceride level (Rvb = 120 +/- 11.2 mg/dl) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA2212892 | F | Antidyslipidemic activity in high fat diet-induced obese mouse assessed as decrease in total blood cholesterol level (Rvb = 160 +/- 13.9 mg/dl) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | small-molecule physicochemical format | AstraZeneca Deposited Data | |||
| 20. | ALA5138472 | F | Inhibition of HCV replication in human Huh7.5 cells after 3 hrs by renilla luciferase assay | Hepacivirus hominis | 1 | cell-based format | Scientific Literature |
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