# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2215305 | ADME | Terminal half life in Sprague-Dawley rat at 5 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
2. | ALA2215307 | ADME | Oral bioavailability in Sprague-Dawley rat at 5 mg/kg | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
3. | ALA2215309 | ADME | Drug absorption in Sprague-Dawley rat portal vein at 5 mg/kg, po | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
4. | ALA2215311 | ADME | AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
5. | ALA2215313 | ADME | AUC in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
6. | ALA2215315 | ADME | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA2202978 | organism-based format | Scientific Literature | |
7. | ALA2215317 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A R115K mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
8. | ALA2215318 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A D168V mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
9. | ALA2215319 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A D168A mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
10. | ALA2215320 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A A156V mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
11. | ALA2215321 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A A156T mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
12. | ALA2215322 | Functional | Antiviral activity against HCV subtype 1b expressing NS3/4A A156S mutant protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
13. | ALA2215323 | Functional | Antiviral activity against HCV subtype 1b expressing wild type NS3/4A protease infected in ET cells after 72 hrs | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
14. | ALA2215324 | Functional | Antiviral activity against HCV subtype 1b infected in human hepatoma cells | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
15. | ALA2215325 | Functional | Antiviral activity against HCV subtype 1a infected in human hepatoma cells | Hepacivirus hominis | 19 | ALA2202978 | organism-based format | Scientific Literature | |
16. | ALA2215774 | Binding | Inhibition of HCV subtype 1a NS3/4A protease (Ac-DE-Dap(QXL520)-EE-Abu-psi-[COO]-ASC(5-FAMsp)-NH2 as substrate by FRET analysis | Hepatitis C virus subtype 1a | 19 | ALA2202978 | assay format | Scientific Literature |