# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3050827 | F | Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 72 hr by NCCLS M27-A broth microdilution method | Botrytis cinerea | 16 | organism-based format | Scientific Literature | ||
2. | ALA3050828 | F | Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 48 hr by NCCLS M27-A broth microdilution method | Botrytis cinerea | 15 | organism-based format | Scientific Literature | ||
3. | ALA3050834 | F | Antifungal activity against Diaporthe ampelina assessed as growth inhibition after 144 hr by NCCLS M27-A broth microdilution method | Diaporthe ampelina | 4 | organism-based format | Scientific Literature | ||
4. | ALA3050835 | P | Octanol-water partition coefficient, log P of the compound by HPLC analysis | 24 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4340443 | A | Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISA | Ovis aries | 6 | single protein format | Scientific Literature | ||
6. | ALA4340444 | B | Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISA | Homo sapiens | 6 | single protein format | Scientific Literature | ||
7. | ALA4340446 | B | Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISA | Homo sapiens | 6 | single protein format | Scientific Literature | ||
8. | ALA4340447 | A | Cytotoxicity against human THP1 cells assessed as reduction in cell viability incubated for 24 hrs by WST1 dye based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
9. | ALA4340448 | B | Inhibition of LPS-stimulation dependent TLR4-induced NF-kappaB/AP-1 signaling cascade in human THP1-XBlue-MD2-CD14 cells at 1 uM pre-incubated for 1 hr before LPS-stimulation for 24 hrs by spectrophotometry | Homo sapiens | 6 | assay format | Scientific Literature | ||
10. | ALA4340449 | F | Antiinflammatory activity in PMA-differentiated human THP1 cells assessed as inhibition of TNFalpha production at 1 uM pre-incubated for 1 hr before LPS-stimulation for 24 hrs by ELISA | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA4340450 | F | Antiinflammatory activity in PMA-differentiated human THP1 cells assessed as inhibition of IL-1beta production at 1 uM pre-incubated for 1 hr before LPS-stimulation for 24 hrs by ELISA | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA4340455 | B | Inhibition of IkappaBalpha degradation in LPS-stimulated human THP1-XBlue-MD2-CD14 cells at 1 uM pre-incubated for 1 hr before LPS-stimulation for 30 mins by Western blot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA4340456 | B | Inhibition of ERK1/2 phosphorylation in LPS-stimulated human THP1-XBlue-MD2-CD14 cells at 1 uM pre-incubated for 1 hr before LPS-stimulation for 30 mins by Western blot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA4340457 | B | Inhibition of p38 phosphorylation in LPS-stimulated human THP1-XBlue-MD2-CD14 cells at 1 uM pre-incubated for 1 hr before LPS-stimulation for 30 mins by Western blot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA4340458 | B | Inhibition of JNK phosphorylation in LPS-stimulated human THP1-XBlue-MD2-CD14 cells at 1 uM pre-incubated for 1 hr before LPS-stimulation for 30 mins by Western blot analysis | Homo sapiens | 1 | assay format | Scientific Literature |