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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA659309 | Binding | Binding affinity towards mouse Caspase-1 | 65 | ALA1146752 | single protein format | Scientific Literature | ||
2. | ALA658629 | Binding | Binding affinity towards human caspase 3 | 71 | ALA1146752 | single protein format | Scientific Literature | ||
3. | ALA658653 | Binding | Binding affinity towards human Caspase-6 | 65 | ALA1146752 | single protein format | Scientific Literature | ||
4. | ALA659705 | Binding | Binding affinity towards human caspase 8 | 71 | ALA1146752 | single protein format | Scientific Literature | ||
5. | ALA702378 | Functional | Inhibitory activity evaluated against human jurkat cell line in cellular assay | Homo sapiens | 52 | ALA1146752 | cell-based format | Scientific Literature | |
6. | ALA782755 | Functional | Inhibitory activity evaluated against rat Con A embryonic cortical neurons in cellular assay | Rattus norvegicus | 71 | ALA1146752 | organism-based format | Scientific Literature | |
7. | ALA803948 | Functional | Inhibitory activity was evaluated against human SKW 6.4 cell line in cellular assay | Homo sapiens | 44 | ALA1146752 | cell-based format | Scientific Literature | |
8. | ALA807817 | Functional | Inhibitory activity evaluated against human THP-1 cell line in cellular assay | Homo sapiens | 63 | ALA1146752 | cell-based format | Scientific Literature | |
9. | ALA3881121 | Binding | Inhibition of mouse recombinant ICE pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Mus musculus | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
10. | ALA3881122 | Binding | Inhibition of mouse recombinant ICE assessed as ratio of irreversible rate constant K3 to dissociation constant of the reversible binding step Ki pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Mus musculus | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
11. | ALA3881123 | Binding | Inhibition of recombinant CPP32 (unknown origin) pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
12. | ALA3881124 | Binding | Inhibition of recombinant CPP32 (unknown origin) assessed as ratio of irreversible rate constant K3 to dissociation constant of the reversible binding step Ki pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
13. | ALA3881125 | Binding | Inhibition of recombinant MCH2 (unknown origin) pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
14. | ALA3881126 | Binding | Inhibition of recombinant MCH2 (unknown origin) assessed as ratio of irreversible rate constant K3 to dissociation constant of the reversible binding step Ki pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
15. | ALA3881127 | Binding | Inhibition of recombinant MCH5 (unknown origin) pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data | |
16. | ALA3881128 | Binding | Inhibition of recombinant MCH5 (unknown origin) assessed as ratio of irreversible rate constant K3 to dissociation constant of the reversible binding step Ki pre-incubated for 60 mins with Acetyl-Tyr-Val-Ala-Asp-amino-4-methylcoumarin substrate followed by enzyme addition by fluorescence based assay | Homo sapiens | 77 | ALA3880422 | single protein format | Patent Bioactivity Data |