# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3054873 | B | Binding affinity to Ovis aries (sheep) brain tubulin assessed as intrinsic tryptophan fluorescence at 25 to 50 uM after 30 min by far-UV CD spectrum analysis | Ovis aries | 1 | ALA3045461 | assay format | Scientific Literature | |
2. | ALA3054874 | B | Binding affinity to Ovis aries (sheep) brain tubulin assessed as intrinsic tryptophan fluorescence after 30 min by fluorescence spectroscopic analysis | Ovis aries | 1 | ALA3045461 | tissue-based format | Scientific Literature | |
3. | ALA3054876 | B | Binding affinity to Ovis aries (sheep) brain tubulin assessed as increase in fluorescent intensity at 1:1 compound protein ratio after 30 min by fluorescence spectroscopic analysis | Ovis aries | 1 | ALA3045461 | assay format | Scientific Literature | |
4. | ALA3054877 | F | Cytotoxicity against Homo sapiens (human) SK-N-MC cells after 72 hr by MTT assay | Homo sapiens | 6 | ALA3045461 | cell-based format | Scientific Literature | |
5. | ALA3054878 | F | Cytotoxicity against Homo sapiens (human) K562 cells after 72 hr by MTT assay | Homo sapiens | 6 | ALA3045461 | cell-based format | Scientific Literature | |
6. | ALA3054879 | B | Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as reduction of length of microtubule filament at 20 to 30 uM after 15 min by transmission electron microscopy analysis | Ovis aries | 1 | ALA3045461 | assay format | Scientific Literature | |
7. | ALA3054880 | B | Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly at 30 uM after 30 min by CD spectra analysis | Ovis aries | 1 | ALA3045461 | assay format | Scientific Literature | |
8. | ALA3054887 | B | Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 30 min by CD spectra analysis | Ovis aries | 1 | ALA3045461 | assay format | Scientific Literature | |
9. | ALA3054888 | B | Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopic analysis | Ovis aries | 6 | ALA3045461 | assay format | Scientific Literature |