# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA652451 | B | Displacement of [3H]flunitrazepam from GABA-A benzodiazepine receptor of rat cortical membranes | Rattus norvegicus | 14 | ALA1129735 | cell membrane format | Scientific Literature | |
2. | ALA651179 | B | Displacement of [3H]flunitrazepam from GABA-A benzodiazepine receptor of rat cortical membranes | Rattus norvegicus | 64 | ALA1132620 | cell membrane format | Scientific Literature | |
3. | ALA656593 | F | In vitro GABA-mediated chloride current in A293 cells expressing GABA-A benzodiazepine receptor alpha-1-beta-2-gamma-2 subunits at 5 uM | 63 | ALA1132620 | cell-based format | Scientific Literature | ||
4. | ALA680658 | B | Inhibition of [3H]flunitrazepam binding to GABA-A receptor of rat cortical membranes | Rattus norvegicus | 47 | ALA1129282 | cell membrane format | Scientific Literature | |
5. | ALA685373 | B | In vitro inhibition of [35S]TBPS binding in rat brain membranes, activity expressed as [35S]TBPS shift value | Rattus norvegicus | 47 | ALA1129282 | cell membrane format | Scientific Literature | |
6. | ALA681620 | F | Binding to GABA-A receptor complex relative to TBPS binding to picrotoxin convulsant site | Rattus norvegicus | 5 | ALA1129735 | assay format | Scientific Literature | |
7. | ALA677789 | F | In vitro efficacy for GABA-A alpha-1-beta-2-gamma-2 subtype expressed in A293 cells in Cl- current assay | Rattus norvegicus | 13 | ALA1129735 | cell-based format | Scientific Literature | |
8. | ALA678632 | B | Displacement of [3H]flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cells | 3 | ALA1129282 | cell-based format | Scientific Literature | ||
9. | ALA680443 | B | Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes | Rattus norvegicus | 13 | ALA1129735 | cell-based format | Scientific Literature | |
10. | ALA683021 | B | Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cells | 2 | ALA1129282 | cell-based format | Scientific Literature | ||
11. | ALA715518 | F | Acute electroshock physical dependence activity was evaluated; IA=Inactive | Mus musculus | 1 | ALA1129282 | organism-based format | Scientific Literature | |
12. | ALA717703 | F | Ethanol potentiation activity was measured as loss of righting reflex in male CF-1 mice after oral administration | Mus musculus | 12 | ALA1129282 | organism-based format | Scientific Literature | |
13. | ALA717704 | F | Ethanol potentiation activity was measured as loss of traction response in male CF-1 mice after oral administration | Mus musculus | 13 | ALA1129282 | organism-based format | Scientific Literature | |
14. | ALA719592 | F | In vivo antagonistic activity against benzodiazepine in mice after ip administration | Mus musculus | 10 | ALA1129282 | organism-based format | Scientific Literature | |
15. | ALA722166 | F | Ability to antagonize the muscle relaxation effect in mice caused by a benzodiazepine full agonist, triazolam. | Mus musculus | 51 | ALA1132620 | organism-based format | Scientific Literature | |
16. | ALA732789 | F | In vivo acute electroshock physical dependence activity in mice; Not active. | Mus musculus | 18 | ALA1132620 | organism-based format | Scientific Literature | |
17. | ALA731773 | F | In vivo efficacy is evaluated by percent control of cerebellar GMP levels in (drug+stress) treated mice/mice under stress | Mus musculus | 34 | ALA1132620 | organism-based format | Scientific Literature | |
18. | ALA781850 | F | Antagonism of metrazole-induced clonic convulsions in rats after ip injection | Rattus norvegicus | 7 | ALA1129735 | organism-based format | Scientific Literature | |
19. | ALA779700 | F | In vivo efficacy evaluated for ability to antagonize metrazole induced clonic convulsions in rat after ip injection | Rattus norvegicus | 63 | ALA1132620 | organism-based format | Scientific Literature | |
20. | ALA787779 | F | Antagonistic activity against metrazole-induced clonic convulsions in rat after ip injection | Rattus norvegicus | 43 | ALA1129282 | organism-based format | Scientific Literature |