# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3058615 | F | Antifeedant activity against 4th instar larvae of Achaea janata in Riclmus cammunls leaves assessed as total leaf disc consumed at 200 ppm after 24 hrs by leaf disc bioassay | Achaea janata | 21 | ALA3045093 | organism-based format | Scientific Literature | |
2. | ALA3788408 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 26 | ALA3784979 | cell-based format | Scientific Literature | |
3. | ALA3788409 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 26 | ALA3784979 | cell-based format | Scientific Literature | |
4. | ALA3788410 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 26 | ALA3784979 | cell-based format | Scientific Literature | |
5. | ALA3788655 | F | Antiproliferative activity against p53 deficient human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 7 | ALA3784979 | cell-based format | Scientific Literature | |
6. | ALA3788658 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G1 phase at 0.58 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 31.72 +/- 2.21%) | Homo sapiens | 1 | ALA3784979 | cell-based format | Scientific Literature | |
7. | ALA3788662 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at S phase at 0.58 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 40.55 +/- 1.36%) | Homo sapiens | 1 | ALA3784979 | cell-based format | Scientific Literature | |
8. | ALA3792063 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G2 phase at 0.58 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 27.73 +/- 3.56%) | Homo sapiens | 1 | ALA3784979 | cell-based format | Scientific Literature | |
9. | ALA3792067 | T | Toxicity in ip dosed BALB/c mouse by bliss test | Mus musculus | 3 | ALA3784979 | organism-based format | Scientific Literature | |
10. | ALA3792070 | F | Antitumor activity against human HCT116 cells xenografted in ip dosed BALB/c mouse assessed as tumor growth inhibition administered twice weekly for 4 weeks measured 24 hrs post last dose | Homo sapiens | 3 | ALA3784979 | organism-based format | Scientific Literature | |
11. | ALA3792071 | T | Toxicity in BALB/c mouse assessed as change in body weight at 100 to 200 mg/kg, ip twice weekly for 4 weeks measured 24 hrs post last dose | Mus musculus | 3 | ALA3784979 | organism-based format | Scientific Literature | |
12. | ALA3792073 | B | Inhibition of MDM2/P53 protein interaction in human HCT116 cells at 0.5 to 5 uM after 24 hrs by immunoprecipitation analysis | Homo sapiens | 1 | ALA3784979 | cell-based format | Scientific Literature |