| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA641402 | F | In vitro efficacy calculated by chlorine current assay on alpha-1-beta-2-gamma-2 (GABA-A) receptor subtype | 52 | assay format | Scientific Literature | |||
| 2. | ALA652450 | B | Binding affinity against benzodiazepine receptor (BzR) in rat cortical membranes determined by competition experiments with radiolabeled [3H]flunitrazepam (Fnz) | Rattus norvegicus | 53 | cell membrane format | Scientific Literature | ||
| 3. | ALA652451 | B | Displacement of [3H]flunitrazepam from GABA-A benzodiazepine receptor of rat cortical membranes | Rattus norvegicus | 14 | cell membrane format | Scientific Literature | ||
| 4. | ALA651179 | B | Displacement of [3H]flunitrazepam from GABA-A benzodiazepine receptor of rat cortical membranes | Rattus norvegicus | 64 | cell membrane format | Scientific Literature | ||
| 5. | ALA656593 | F | In vitro GABA-mediated chloride current in A293 cells expressing GABA-A benzodiazepine receptor alpha-1-beta-2-gamma-2 subunits at 5 uM | 63 | cell-based format | Scientific Literature | |||
| 6. | ALA680658 | B | Inhibition of [3H]flunitrazepam binding to GABA-A receptor of rat cortical membranes | Rattus norvegicus | 47 | cell membrane format | Scientific Literature | ||
| 7. | ALA685373 | B | In vitro inhibition of [35S]TBPS binding in rat brain membranes, activity expressed as [35S]TBPS shift value | Rattus norvegicus | 47 | cell membrane format | Scientific Literature | ||
| 8. | ALA678604 | F | Binding to GABA-A receptor complex relative to TBPS binding to picrotoxin convulsant site | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 9. | ALA678605 | B | In vitro efficacy by [35S]t-butyl-bicyclophosphorothionate (TBPS) binding to the picrotoxin convulsant site on the GABA-A receptor chloride complex. | 51 | protein complex format | Scientific Literature | |||
| 10. | ALA677789 | F | In vitro efficacy for GABA-A alpha-1-beta-2-gamma-2 subtype expressed in A293 cells in Cl- current assay | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 11. | ALA677024 | B | Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cells | 6 | cell-based format | Scientific Literature | |||
| 12. | ALA680443 | B | Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 13. | ALA683024 | B | Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cells | 4 | cell-based format | Scientific Literature | |||
| 14. | ALA685347 | B | Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cells | 6 | cell-based format | Scientific Literature | |||
| 15. | ALA713085 | F | Acute electroshock physical dependence activity was evaluated; IA=Inactive | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA716321 | F | In vivo antagonistic activity against benzodiazepine in mice | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA717704 | F | Ethanol potentiation activity was measured as loss of traction response in male CF-1 mice after oral administration | Mus musculus | 13 | organism-based format | Scientific Literature | ||
| 18. | ALA717705 | F | Ethanol potentiation was measured against LORR | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA722166 | F | Ability to antagonize the muscle relaxation effect in mice caused by a benzodiazepine full agonist, triazolam. | Mus musculus | 51 | organism-based format | Scientific Literature | ||
| 20. | ALA732789 | F | In vivo acute electroshock physical dependence activity in mice; Not active. | Mus musculus | 18 | organism-based format | Scientific Literature |
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