| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3078156 | B | Ratio of metformin activity to compound activity for inhibition of PTP1B in Rattus norvegicus (rat) L6 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3077708 | B | Ratio of rosiglitazone activity to compound activity for inhibition of PTP1B in Rattus norvegicus (rat) L6 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3077709 | F | Antihyperglycemic activity in sucrose-challenged streptozotocin-induced Rattus norvegicus Wistar albino (rat) diabetic model assessed as glucose reduction at 30 mg/kg measured at 24 hr relative to control | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 4. | ALA3077710 | F | Antihyperglycemic activity in sucrose-challenged streptozotocin-induced Rattus norvegicus Wistar albino (rat) diabetic model assessed as glucose reduction at 30 mg/kg measured at 5 hr relative to control | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA3077711 | F | Antihyperglycemic activity in sucrose-loaded Rattus norvegicus Wistar albino (rat) diabetic model assessed as glucose reduction at 30 mg/kg measured at 24 hr relative to control | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA3077712 | F | Antihyperglycemic activity in sucrose-loaded Rattus norvegicus Wistar albino (rat) diabetic model assessed as glucose reduction at 30 mg/kg measured at 5 hr relative to control | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA3077713 | B | Inhibition of Homo sapiens (human) recombinant PTP1B at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA3077716 | B | Inhibition of PTP1B in Rattus norvegicus (rat) L6 cells assessed as cellular 2-deoxy-D-[U-14C]glucose uptake at 10 to 50 uM after 18 hr relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3076998 | B | Inhibition of PTP1B in Rattus norvegicus (rat) L6 cells assessed as increase in 2-deoxy-D-[U-14C]-glucose uptake at 50 uM after 18 hr relative to control | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA3076999 | B | Inhibition of Homo sapiens (human) recombinant PTP1B assessed as decrease in free phosphate release at 10 uM by malachite staining relative to control | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 11. | ALA3090066 | B | Inhibition of recombinant human PTP1B at 10 uM by malachite green assay relative to control | Homo sapiens | 13 | single protein format | Scientific Literature |
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