# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA698897 | F | In vitro inhibition of Human Leukocyte Elastase enzyme in whole blood stimulated with A-23187 (at dose 3 uM) | 1 | ALA1128120 | tissue-based format | Scientific Literature | ||
2. | ALA698903 | B | Compound was tested for inhibition of Human Leukocyte Elastase enzyme, expressed in term of bimolecular rate constant (Kinact/Ki) | 9 | ALA1128120 | assay format | Scientific Literature | ||
3. | ALA821528 | F | Effective dose required to in vivo inhibition in HLE-induced hamster lung hemorrhage when given orally 5 hr before the enzyme | Cricetulus griseus | 1 | ALA1128120 | organism-based format | Scientific Literature | |
4. | ALA5247062 | A | Oral bioavailability in rat | Rattus norvegicus | 16 | ALA5244275 | organism-based format | Scientific Literature | |
5. | ALA5247091 | A | Oral bioavailability in monkey | Macaca mulatta | 3 | ALA5244275 | organism-based format | Scientific Literature | |
6. | ALA5247105 | B | Time-dependent inhibition of human leukocyte elastase assessed as observed binding constant | Homo sapiens | 4 | ALA5244275 | single protein format | Scientific Literature | |
7. | ALA5247107 | A | Terminal half-life in iv dosed rat | Rattus norvegicus | 1 | ALA5244275 | organism-based format | Scientific Literature | |
8. | ALA5247108 | A | Terminal half-life in iv dosed rhesus monkey | Macaca mulatta | 1 | ALA5244275 | organism-based format | Scientific Literature | |
9. | ALA5247110 | A | Terminal half-life in rhesus monkey at 40 mg/kg, po | Macaca mulatta | 2 | ALA5244275 | organism-based format | Scientific Literature |