# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3075343 | B | Inhibition of Rattus norvegicus (rat) lens aldose reductase | Rattus norvegicus | 38 | single protein format | Scientific Literature | ||
2. | ALA3378918 | B | Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding potential of -80 mV by electrophysiology | Homo sapiens | 21 | assay format | Scientific Literature | ||
3. | ALA3378919 | B | Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding potential of -80 mV by electrophysiology relative to control | Homo sapiens | 18 | assay format | Scientific Literature | ||
4. | ALA3378921 | B | Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of ACh-induced current at holding potential of -80 mV measured as ACh EC50 at 1 uM by electrophysiology (Rvb = 176 uM) | Homo sapiens | 2 | assay format | Scientific Literature | ||
5. | ALA3378922 | B | Activity at human alpha4beta2 nACHR expressed in Xenopus oocyte assessed as induction of current at holding potential of -80 mV at 10 uM by electrophysiology relative to ACh | Homo sapiens | 2 | assay format | Scientific Literature | ||
6. | ALA3378923 | B | Activity at human alpha3beta4 nACHR expressed in Xenopus oocyte assessed as induction of current at holding potential of -80 mV at 10 uM by electrophysiology relative to ACh | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA3378924 | B | Agonist activity at alpha7 nACHR in bovine adrenal medulla chromaffin cells assessed as potentiation of choline-induced catecholamine output at 30 uM | Bos taurus | 1 | assay format | Scientific Literature | ||
8. | ALA3378925 | B | Agonist activity at alpha7 nACHR in bovine adrenal medulla chromaffin cells assessed as potentiation of choline-induced catecholamine output at 30 uM by single cell amperometry | Bos taurus | 1 | assay format | Scientific Literature | ||
9. | ALA3378926 | A | Cytotoxicity against HEK293 cells up to 30 uM after 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA3378930 | A | Effect on Sprague-Dawley rat atrium assessed as force or beating frequency at 0.01 to 100 uM | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
11. | ALA3378931 | A | Effect on Sprague-Dawley rat vas deferens assessed as spontaneous and voltage-stimulated contraction at 0.01 to 100 uM | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
12. | ALA3378932 | A | Effect on Sprague-Dawley rat ileum assessed as peristaltic force or frequency at 0.01 to 100 uM | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
13. | ALA3378933 | A | Effect on Sprague-Dawley rat phrenic-diaphragm muscle at 0.01 to 100 uM | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
14. | ALA3378944 | B | Agonist activity at human alpha7 nACHR expressed in Xenopus oocyte assessed as induction of current at holding potential of -80 mV at 10 uM by electrophysiology relative to ACh | Homo sapiens | 2 | assay format | Scientific Literature | ||
15. | ALA3784400 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
16. | ALA3784401 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature |