| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA653092 | F | Cell growth toxicity against CEM cells after treatment with compound for 72 hours | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA655269 | T | Toxic concentration, in CEM cells estimated by the XTT assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA683693 | F | Tested in vitro against human immunodeficiency virus (HIV) infected CEM cells using XTT assay (LAV-BRU strain) | Human immunodeficiency virus 1 | 9 | organism-based format | Scientific Literature | ||
| 4. | ALA695734 | F | Tested in vitro against HSV 2 G strain in vero cells | Human alphaherpesvirus 2 | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA878310 | A | Tested in vitro against HSV 2 G strain in vero cells | Human alphaherpesvirus 2 | 18 | organism-based format | Scientific Literature | ||
| 6. | ALA697583 | F | Tested in vitro against HCMV AD-169 strain in MRC-5 cells | Human betaherpesvirus 5 | 12 | organism-based format | Scientific Literature | ||
| 7. | ALA878187 | A | Tested in vitro against HCMV AD-169 strain in MRC-5 cells | Human betaherpesvirus 5 | 16 | organism-based format | Scientific Literature | ||
| 8. | ALA840452 | F | Ratio between TC50 against human immunodeficiency virus infected CEM cells and IC50 against CEM cells | 15 | cell-based format | Scientific Literature | |||
| 9. | ALA1768312 | F | Antiviral activity against HIV1 infected in human MT4 cells assessed as inhibition of virus-induced cytopathicity | Human immunodeficiency virus 1 | 6 | organism-based format | Scientific Literature | ||
| 10. | ALA1768313 | A | Cytotoxicity against human MT4 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA2423188 | B | Inhibition of recombinant Plasmodium vivax HGXPRT expressed in Escherichia coli by spectrophotometric analysis | Plasmodium vivax | 10 | assay format | Scientific Literature | ||
| 12. | ALA2423189 | B | Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA2423190 | B | Inhibition of recombinant Plasmodium falciparum HGXPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysis | Plasmodium falciparum | 10 | cell-based format | Scientific Literature | ||
| 14. | ALA4040184 | F | Antiviral activity against CXCR4-tropic HIV-1 NL4-3 infected in human TZM-bl cells assessed as inhibition of virus-induced cytopathic effect preincubated with cells for 30 mins followed by viral infection measured after 48 hrs in presence of p-24 HIV-1 Ag by luciferase reporter gene assay | Human immunodeficiency virus 1 | 17 | cell-based format | Scientific Literature | ||
| 15. | ALA4040185 | F | Antiviral activity against CCR5 tropic HIV1 BaL infected in human TZM-bl cells assessed as inhibition of virus-induced cytopathic effect preincubated with cells for 30 mins followed by viral infection measured after 48 hrs in presence of p-24 HIV-1 Ag by luciferase reporter gene assay | Human immunodeficiency virus 1 | 17 | cell-based format | Scientific Literature | ||
| 16. | ALA4040186 | A | Cytotoxicity against human TZM-bl cells assessed as cell viability by tetrazolium dye assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 17. | ALA4040187 | F | Antiviral activity against CXCR4-tropic HIV-1 NL4-3 infected in human PHA-stimulated PBMC assessed as inhibition of viral replication by measuring reduction in p24 antigen production preincubated with cells for 30 mins followed by viral infection measured on day 10 post infection in presence of IL-2 by ELISA | Human immunodeficiency virus 1 | 11 | assay format | Scientific Literature | ||
| 18. | ALA4040188 | F | Antiviral activity against CCR5 tropic HIV1 BaL infected in human PHA-stimulated PBMC assessed as inhibition of viral replication by measuring reduction in p24 antigen production preincubated with cells for 30 mins followed by viral infection measured on day 10 post infection in presence of IL-2 by ELISA | Human immunodeficiency virus 1 | 11 | assay format | Scientific Literature | ||
| 19. | ALA4040189 | A | Cytotoxicity against human PHA-stimulated PBMC assessed as cell viability by tetrazolium dye assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 20. | ALA4040190 | T | Selectivity index, ratio of CC50 for human TZM-bl cells to EC50 for CXCR4-tropic HIV-1 NL4-3 infected in human TZM-bl cells | 17 | cell-based format | Scientific Literature |
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