# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3073161 | Functional | Increase in survival of transgenic Caenorhabditis elegans CL2006 expressing human amyloid beta42 at 123 ug/ml | Caenorhabditis elegans | 1 | ALA3045344 | organism-based format | Scientific Literature | |
2. | ALA3073163 | Binding | Induction of amyloid beta (1-42) (unknown origin) oligomer formation after 48 hr by silver staining | Homo sapiens | 1 | ALA3045344 | single protein format | Scientific Literature | |
3. | ALA3073165 | Binding | Stabilization of random coil conformation of amyloid beta (1-42) (unknown origin) after 3 days by CD spectroscopy | Homo sapiens | 3 | ALA3045344 | single protein format | Scientific Literature | |
4. | ALA3073166 | Binding | Binding affinity to amyloid beta (1-42) (unknown origin) assessed as increase in hydrophobic site exposure at Abeta42/compound molar ratio of 1:5 after 3 days by ANS fluorescence analysis | Homo sapiens | 3 | ALA3045344 | assay format | Scientific Literature | |
5. | ALA3073167 | Binding | Binding affinity to amyloid beta (1-42) (unknown origin) assessed as increase in hydrophobic site exposure at Abeta42/compound molar ratio of 1:1 after 3 days by ANS fluorescence analysis | Homo sapiens | 3 | ALA3045344 | assay format | Scientific Literature | |
6. | ALA3073169 | Binding | Inhibition of amyloid beta (1-42) (unknown origin) assembly assessed as decrease in fibril formation after 3 days by ThT stain based fluorescence microscopy | Homo sapiens | 2 | ALA3045344 | single protein format | Scientific Literature | |
7. | ALA3073170 | Binding | Inhibition of amyloid beta (1-42) (unknown origin) fibril formation at Abeta42/compound molar ratio of 1:5 after 3 days by thioflavin T fluorescence method | Homo sapiens | 3 | ALA3045344 | single protein format | Scientific Literature | |
8. | ALA3073171 | Binding | Inhibition of amyloid beta (1-42) (unknown origin) fibril formation at Abeta42/compound molar ratio of 1:1 after 3 days by thioflavin T fluorescence method | Homo sapiens | 3 | ALA3045344 | single protein format | Scientific Literature | |
9. | ALA3068872 | Binding | Induction of amyloid beta (1-42) (unknown origin) aggregation at Abeta42/compound molar ratio of 1:5 after 3 days by turbidity based assay | Homo sapiens | 2 | ALA3045344 | single protein format | Scientific Literature | |
10. | ALA3068873 | Binding | Induction of amyloid beta (1-42) (unknown origin) aggregation at Abeta42/compound molar ratio of 1:1 after 3 days by turbidity based assay | Homo sapiens | 2 | ALA3045344 | single protein format | Scientific Literature |