| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA762661 | Binding | Inhibition of Human Leukocyte Elastase | 1 | ALA1130215 | single protein format | Scientific Literature | ||
| 2. | ALA4713847 | Binding | Inhibition KCN-induced elastase like activity in human U-937 cells at 0.01 to 100 uM using substrate MAAPV | Homo sapiens | 1 | ALA4706679 | cell-based format | Scientific Literature | |
| 3. | ALA4713849 | Functional | Protection against KCN-induced necrosis in human PC-12 cells assessed as reduction in KCN-induced cell death at 10 to 300 uM incubated for 5 hrs by LDH release assay | Homo sapiens | 3 | ALA4706679 | cell-based format | Scientific Literature | |
| 4. | ALA4713851 | Toxicity | Toxicity in sham control C57BL/6J mouse at 100 ug, icv | Mus musculus | 1 | ALA4706679 | assay format | Scientific Literature | |
| 5. | ALA4713852 | Functional | Protection against necrosis in C57BL/6J mouse model of traumatic brain injury assessed as decrease in neuronal damage in brain at 100 ug, icv measured 1 hr post injury by neurological severity score based analysis | Mus musculus | 1 | ALA4706679 | organism-based format | Scientific Literature | |
| 6. | ALA4713853 | Functional | Protection against necrosis in C57BL/6J mouse model of traumatic brain injury assessed as decrease in necrotic space in brains at 100 ug, icv measured 24 hrs post injury by TTC staining based analysis | Mus musculus | 1 | ALA4706679 | organism-based format | Scientific Literature | |
| 7. | ALA5041633 | Binding | Inhibition of elastase (unknown origin) at 2.5 uM by fluorescence microtiter plate method relative to control | Homo sapiens | 1 | ALA5038647 | assay format | Scientific Literature |
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