# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2317024 | B | Inhibition of AGT in human DU145 cells assessed as potentiation of laromustine-induced cytotoxicity under hypoxic condition at >10 uM treated 4 hrs prior to laromustine treatment measured after 24 hrs by clonogenic assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA2317025 | A | Prodrug activation in human DU145 cells assessed as O6-benzylguanine formation under normoxic condition at 50 uM over 3 hrs by HPLC analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2317026 | A | Prodrug activation in mouse EMT6 cells assessed as O6-benzylguanine formation under normoxic condition at 50 uM after 3 hrs by HPLC analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA2317027 | A | Prodrug activation in mouse EMT6 cells assessed as O6-benzylguanine formation under hypoxic condition at 50 uM after 3 hrs by HPLC analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA2317028 | B | Inhibition of AGT in human DU145 cells assessed as potentiation of laromustine-induced cytotoxicity under normoxic condition up to 10 uM treated 4 hrs prior to laromustine treatment measured after 24 hrs by clonogenic assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2317029 | B | Inhibition of AGT in human DU145 cells assessed as potentiation of laromustine-induced cytotoxicity under hypoxic condition up to 10 uM treated 4 hrs prior to laromustine treatment measured after 24 hrs by clonogenic assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA2317032 | A | Prodrug activation in human DU145 cells assessed as O6-benzylguanine formation under hypoxic condition at 50 uM over 3 hrs by HPLC analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |