| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2318754 | B | Selectivity ratio of EC50 for human 3:2 alpha4beta2 nAChR to EC50 for human 2:3 alpha4beta2 nAChR | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 2. | ALA2318755 | B | Agonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells after 30 mins by FLIPR membrane potential blue assay relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA2318757 | B | Agonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells after 30 mins by FLIPR membrane potential blue assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA2318758 | B | Agonist activity at human 3:2 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique relative to acetylcholine | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2318759 | B | Partial agonist activity at human 2:3 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique relative to acetylcholine | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA2318760 | B | Agonist activity at human 3:2 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2318761 | B | Partial agonist activity at human 2:3 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA2318762 | B | Selectivity ratio of Ki for rat recombinant alpha4beta4 nAChR to Ki for rat recombinant alpha4beta2 nAChR | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 9. | ALA2318763 | B | Selectivity ratio of Ki for rat recombinant alpha3beta4 nAChR to Ki for rat recombinant alpha4beta2 nAChR | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 10. | ALA2318764 | B | Displacement of [3H]epibatidine from rat recombinant alpha4beta4 nAChR expressed in HEK293 cells after 4 hrs by scintillation counting analysis | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 11. | ALA2318765 | B | Displacement of [3H]epibatidine from rat recombinant alpha3beta4 nAChR expressed in HEK293 cells after 4 hrs by scintillation counting analysis | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA2318766 | B | Displacement of [3H]MLA from rat nAChR alpha7 linked to ion channel portion of 5-HT3A receptor expressed in human tsA-201 cells after 2.5 hrs by scintillation counting analysis | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA2318767 | B | Displacement of [3H]epibatidine from rat recombinant alpha4beta2 nAChR expressed in HEK293 cells after 4 hrs by scintillation counting analysis | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 14. | ALA2318768 | B | Displacement of [3H]epibatidine from Lymnaea stagnalis AChBP linked to ion channel portion of 5-HT3A receptor expressed in HEK293 cells after 4 hrs by scintillation counting analysis | Lymnaea stagnalis | 10 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!