| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2317656 | T | Toxicity in mouse at 20 mg as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2317657 | F | Antiinflammatory activity against MOG peptide-induced experimental autoimmune encephalomyelitis mouse model assessed as CD3 marker measured on day 24 after 2 weeks of treatment (Rvb = 4.8 +/- 0.19 /mm'2) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2317658 | B | Inhibition of PAD4 (unknown origin) at 52 degC | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA2317659 | T | Toxicity in mouse at 10 mg for 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2317660 | B | Inhibition of PAD4 (unknown origin) at 37 degC | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA4029647 | B | Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4029648 | B | Inhibition of full length recombinant human N-terminal GST-tagged PAD4 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethylester as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4029649 | B | Inhibition of human PAD1 using BAEE as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by colorimetric assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 9. | ALA4029650 | F | Antiinflammatory activity in MOG peptide/complete freund's adjuvant/pertussis toxin-induced C57BL/6 mouse autoimmune encephalomyelitis model assessed as improvement in physical disability at 100 mg/kg, ip administered once daily for 40 days measured daily during compound dosing | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4029675 | T | Toxicity in MOG peptide/complete freund's adjuvant/pertussis toxin-induced C57BL/6 mouse autoimmune encephalomyelitis model assessed as change in body weight at 100 mg/kg, ip administered once daily for 40 days measured during compound dosing | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA5035489 | B | Inhibition of PDE4 (unknown origin) by colorimetric assay | Homo sapiens | 6 | protein format | Scientific Literature |
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