# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3390270 | Binding | Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | Homo sapiens | 11 | ALA3351311 | cell-based format | Scientific Literature | |
2. | ALA3390271 | Binding | Inhibition of rat PDE10A expressed in Sf9 cells incubated for 60 mins using [3H]-cAMP substrate by scintillation counting method | Rattus norvegicus | 11 | ALA3351311 | cell-based format | Scientific Literature | |
3. | ALA3390272 | Binding | Selectivity index, ratio of IC50 for rat PDE10A to IC50 for human PDE2A | 11 | ALA3351311 | assay format | Scientific Literature | ||
4. | ALA2319033 | Binding | Inhibition of human recombinant PDE3B expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
5. | ALA2319034 | Binding | Inhibition of human recombinant PDE10A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 15 | ALA2311279 | cell-based format | Scientific Literature | |
6. | ALA2319035 | Binding | Inhibition of human recombinant PDE11A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
7. | ALA2320453 | Binding | Inhibition of human recombinant PDE9A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
8. | ALA2320454 | Binding | Inhibition of human recombinant PDE7A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
9. | ALA2320455 | Binding | Inhibition of human recombinant PDE6AB expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
10. | ALA2320456 | Binding | Inhibition of human recombinant PDE4A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
11. | ALA2320457 | Binding | Inhibition of human recombinant PDE5A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
12. | ALA2320458 | Binding | Inhibition of human recombinant PDE3A expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
13. | ALA2320459 | ADME | Drug uptake in Wistar rat hippocampus at 0.03 mg/kg, iv after 2 to 30 mins | Rattus norvegicus | 1 | ALA2311279 | organism-based format | Scientific Literature | |
14. | ALA2320460 | Binding | Inhibition of human recombinant PDE1B expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA2311279 | cell-based format | Scientific Literature | |
15. | ALA2320461 | ADME | Drug uptake in Wistar rat cortex at 0.03 mg/kg, iv after 2 to 30 mins | Rattus norvegicus | 1 | ALA2311279 | organism-based format | Scientific Literature | |
16. | ALA2320462 | ADME | Drug uptake in Wistar rat striatum at 0.03 mg/kg, iv after 2 to 30 mins | Rattus norvegicus | 1 | ALA2311279 | organism-based format | Scientific Literature | |
17. | ALA2320464 | ADME | Ratio of drug level brain to plasma in Sprague-Dawley rat at 10 mg/kg, sc after 1 hr | Rattus norvegicus | 3 | ALA2311279 | organism-based format | Scientific Literature | |
18. | ALA2320470 | ADME | Plasma concentration in Sprague-Dawley rat at 10 mg/kg, sc after 1 hr | Rattus norvegicus | 3 | ALA2311279 | organism-based format | Scientific Literature | |
19. | ALA2320473 | ADME | Drug level in Sprague-Dawley rat brain at 10 mg/kg, sc after 1 hr | Rattus norvegicus | 3 | ALA2311279 | organism-based format | Scientific Literature | |
20. | ALA2320476 | Binding | Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assay | Rattus norvegicus | 34 | ALA2311279 | cell-based format | Scientific Literature |