# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2319887 | B | Inhibition of tissue factor procoagulant activity in LPS-stimulated human THP1 cells preincubated for 1 hr before LPS addition measured after 5 hrs | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA5251709 | F | Cytotoxicity against vincristine resistant human Eca-109 cells incubated for 48 hrs by CCK-8 method relative to control | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
3. | ALA5251710 | F | Reversal of VCR -resistance in human Eca-109 cells assessed as vincristine IC50 by measuring cell viability incubated for 48 hrs by CCK-8 method (Rvb = 6830.0+/-537.0 nM) | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
4. | ALA5251711 | F | Reversal of vincristine-resistance in human Eca-109 cells assessed as fold reversal by measuring cell viability incubated for 48 hrs by CCK-8 method relative to vincristine alone | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
5. | ALA4339970 | F | Antagonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of SKF38393-induced cAMP accumulation measured after 30 mins | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
6. | ALA4339971 | F | Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for 60 mins at 37 degC followed by 15 mins incubation under room temperature and subsequent dopamine addition measured after 20 secs for 100 secs by calcium-4 dye based FLIPR assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
7. | ALA4339972 | F | Agonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as increase in cAMP accumulation at 10 uM measured after 30 mins | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
8. | ALA4339973 | F | Agonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as increase in calcium flux at 10 uM incubated for 60 mins at 37 degC followed by 15 mins incubation under room temperature measured after 20 secs for 100 secs by calcium-4 dye based FLIPR assay relative to control | Homo sapiens | 18 | cell-based format | Scientific Literature |