| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2320319 | B | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 2. | ALA2320320 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 3. | ALA2321447 | A | Apparent permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 4. | ALA2321448 | A | Metabolic stability in rat liver microsome after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | microsome format | Scientific Literature | ||
| 5. | ALA2321450 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 6. | ALA2321455 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
| 7. | ALA2321456 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 57 | microsome format | Scientific Literature | ||
| 8. | ALA4016019 | B | Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite green assay | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 9. | ALA4016031 | B | Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4046263 | B | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4046264 | B | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4046265 | B | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4046266 | B | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 14. | ALA4046267 | B | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA4046268 | B | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index AT 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | cell-based format | Scientific Literature |
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