# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2320319 | Binding | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM | Rattus norvegicus | 30 | ALA2311383 | microsome format | Scientific Literature | |
2. | ALA2320320 | Binding | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM | Rattus norvegicus | 30 | ALA2311383 | microsome format | Scientific Literature | |
3. | ALA2321447 | ADME | Apparent permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 50 | ALA2311383 | cell-based format | Scientific Literature | |
4. | ALA2321448 | ADME | Metabolic stability in rat liver microsome after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | ALA2311383 | microsome format | Scientific Literature | |
5. | ALA2321450 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 51 | ALA2311383 | cell-based format | Scientific Literature | |
6. | ALA2321455 | Binding | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 56 | ALA2311383 | cell-based format | Scientific Literature | |
7. | ALA2321456 | Binding | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 57 | ALA2311383 | microsome format | Scientific Literature | |
8. | ALA4016019 | Binding | Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite green assay | Homo sapiens | 27 | ALA4014328 | assay format | Scientific Literature | |
9. | ALA4016031 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrs | Homo sapiens | 3 | ALA4014328 | cell-based format | Scientific Literature | |
10. | ALA4046263 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 2 | ALA4043175 | cell-based format | Scientific Literature | |
11. | ALA4046264 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
12. | ALA4046265 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
13. | ALA4046266 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 9 | ALA4043175 | cell-based format | Scientific Literature | |
14. | ALA4046267 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
15. | ALA4046268 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index AT 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature |