# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3377958 | Binding | Inhibition of RAD1 (unknown origin) binding to ssDNA | Homo sapiens | 4 | ALA3352588 | single protein format | Scientific Literature | |
2. | ALA2319658 | Binding | Reversible inhibition of human RAD51 binding to single stranded DNA at 240 uM after 30 mins by fluorescence polarization based assay | Homo sapiens | 1 | ALA2311497 | single protein format | Scientific Literature | |
3. | ALA2319659 | Binding | Time dependent inhibition of human RAD51 binding to single stranded DNA at 59 uM by fluorescence polarization based assay | Homo sapiens | 1 | ALA2311497 | single protein format | Scientific Literature | |
4. | ALA2319660 | Physicochemical | Stability of the compound in DMSO at 10 mg measured after 24 hrs by HPLC analysis in the presence of glutathione | 1 | ALA2311497 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA2319661 | Binding | Inhibition of RAD51 in HEK293 cells assessed as stimulation of single strand annealing at 60 uM after 24 hrs by reporter gene assay based FACS analysis | Homo sapiens | 1 | ALA2311497 | cell-based format | Scientific Literature | |
6. | ALA2319662 | Binding | Inhibition of RAD51-mediated homologous recombination in HEK293 cells at 60 uM after 24 hrs by reporter gene assay based FACS analysis | Homo sapiens | 1 | ALA2311497 | cell-based format | Scientific Literature | |
7. | ALA2319665 | Binding | Competitive inhibition of human RAD51 binding to single stranded DNA after 30 mins by fluorescence polarization based assay in the presence of 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione | Homo sapiens | 1 | ALA2311497 | single protein format | Scientific Literature | |
8. | ALA2319666 | Binding | Irreversible inhibition of human RAD51 binding to single stranded DNA at 240 uM after 30 mins by fluorescence polarization based assay | Homo sapiens | 1 | ALA2311497 | single protein format | Scientific Literature | |
9. | ALA2319669 | Functional | Induction of sensitization to Mitomycin C in HEK293 cells after 24 hrs | Homo sapiens | 27 | ALA2311497 | cell-based format | Scientific Literature | |
10. | ALA2319670 | Functional | Cytotoxicity against HEK293 cells after 24 hrs | Homo sapiens | 27 | ALA2311497 | cell-based format | Scientific Literature | |
11. | ALA2319671 | Binding | Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assay | Homo sapiens | 22 | ALA2311497 | single protein format | Scientific Literature |