| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2319658 | B | Reversible inhibition of human RAD51 binding to single stranded DNA at 240 uM after 30 mins by fluorescence polarization based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2319659 | B | Time dependent inhibition of human RAD51 binding to single stranded DNA at 59 uM by fluorescence polarization based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2319660 | P | Stability of the compound in DMSO at 10 mg measured after 24 hrs by HPLC analysis in the presence of glutathione | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA2319661 | B | Inhibition of RAD51 in HEK293 cells assessed as stimulation of single strand annealing at 60 uM after 24 hrs by reporter gene assay based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2319662 | B | Inhibition of RAD51-mediated homologous recombination in HEK293 cells at 60 uM after 24 hrs by reporter gene assay based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2319665 | B | Competitive inhibition of human RAD51 binding to single stranded DNA after 30 mins by fluorescence polarization based assay in the presence of 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2319666 | B | Irreversible inhibition of human RAD51 binding to single stranded DNA at 240 uM after 30 mins by fluorescence polarization based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2319669 | F | Induction of sensitization to Mitomycin C in HEK293 cells after 24 hrs | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 9. | ALA2319670 | F | Cytotoxicity against HEK293 cells after 24 hrs | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 10. | ALA2319671 | B | Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 11. | ALA3377958 | B | Inhibition of RAD1 (unknown origin) binding to ssDNA | Homo sapiens | 4 | single protein format | Scientific Literature |
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