# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2319199 | F | Antiplasmodial activity against Plasmodium berghei liver stage form transfected in human Huh-7 cells assessed as cell viability after 48 hrs by luciferase reporter gene assay | Plasmodium berghei | 37 | organism-based format | Scientific Literature | ||
2. | ALA2319201 | F | Antiplasmodial activity against CQ-resistant Plasmodium falciparum W2 blood stage form after 48 hrs by FACSort cytometry | Plasmodium falciparum | 35 | organism-based format | Scientific Literature | ||
3. | ALA3225245 | F | Antiplasmodial activity against liver stage of Plasmodium berghei sporozoites expressing firefly luciferase infected in human Huh7 cells assessed as inhibition of parasite development treated 1 hr prior to infection followed by compound replenisment at 24 hrs post-infection measured 48 hrs after infection by bioluminescence analysis | Plasmodium berghei | 12 | organism-based format | Scientific Literature | ||
4. | ALA3225246 | F | Antiplasmodial activity against erythrocyte stage of Plasmodium falciparum W2 assessed as growth inhibition after 48 hrs by flow cytometry | Plasmodium falciparum | 12 | organism-based format | Scientific Literature | ||
5. | ALA3225247 | F | Ratio of primaquine IC50 to compound IC50 against liver stage of Plasmodium berghei sporozoites expressing firefly luciferase infected in human Huh7 cells | Plasmodium berghei | 11 | organism-based format | Scientific Literature | ||
6. | ALA3225248 | A | Cytotoxicity against human HuH7 cells assessed as cell viability by alamarblue assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
7. | ALA4148161 | F | Antiplasmodial activity against erythrocytic stage of Plasmodium falciparum NF54 assessed as reduction in [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting method | Plasmodium falciparum | 65 | organism-based format | Scientific Literature | ||
8. | ALA4148162 | A | Cytotoxicity against rat L6 cells assessed as reduction in cell viability after 70 hrs by Alamar blue assay | Rattus norvegicus | 65 | cell-based format | Scientific Literature | ||
9. | ALA4148163 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for erythrocytic stage of Plasmodium falciparum NF54 | 65 | assay format | Scientific Literature | |||
10. | ALA4253139 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Ra ATCC 25177 after 7 days by Alamar Blue assay | Mycobacterium tuberculosis | 54 | organism-based format | Scientific Literature | ||
11. | ALA4253140 | F | Antimycobacterial activity against Mycobacterium avium complex CIT19/06 clinical isolate after 5 days by Alamar Blue assay | Mycobacterium avium complex sp. | 54 | organism-based format | Scientific Literature | ||
12. | ALA4253141 | F | Antimycobacterial activity against Mycobacterium avium subsp. paratuberculosis CIT03 clinical isolate after 11 days by Alamar Blue assay | Mycobacterium avium subsp. paratuberculosis | 54 | organism-based format | Scientific Literature | ||
13. | ALA4253142 | A | Cytotoxicity against rat L6 cells after 70 hrs by Alamar Blue-based assay | Rattus norvegicus | 36 | cell-based format | Scientific Literature |