# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2328055 | Binding | Selectivity ratio of Ki for human beta-casein/APC-R3 interaction to Ki for human beta-casein/Tcf4 interaction by fluorescence polarization assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
2. | ALA2328056 | Binding | Selectivity ratio of Ki for human beta-casein/E-cadherin interaction to Ki for human beta-casein/Tcf4 interaction by fluorescence polarization assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
3. | ALA2328057 | Binding | Selectivity ratio of Ki for human beta-casein/APC-R3 interaction to Ki for human beta-casein/Tcf4 interaction by alphascreen assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
4. | ALA2328058 | Binding | Selectivity ratio of Ki for human beta-casein/E-cadherin interaction to Ki for human beta-casein/Tcf4 interaction by alphascreen assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
5. | ALA2328059 | Binding | Inhibition of human beta-casein/APC-R3 interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 7 | ALA2321680 | protein format | Scientific Literature | |
6. | ALA2328060 | Binding | Inhibition of human beta-casein/E-cadherin interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
7. | ALA2328061 | Binding | Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 7 | ALA2321680 | protein complex format | Scientific Literature | |
8. | ALA2328062 | Binding | Inhibition of human beta-casein/APC-R3 interaction after 1 hr by alphascreen assay | Homo sapiens | 7 | ALA2321680 | protein format | Scientific Literature | |
9. | ALA2328063 | Binding | Inhibition of human beta-casein/E-cadherin interaction after 1 hr by alphascreen assay | Homo sapiens | 7 | ALA2321680 | assay format | Scientific Literature | |
10. | ALA2328064 | Binding | Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay | Homo sapiens | 7 | ALA2321680 | protein complex format | Scientific Literature | |
11. | ALA3592701 | Binding | Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after 1.5 hrs by FP competitive inhibition assay | Homo sapiens | 34 | ALA3588842 | single protein format | Scientific Literature | |
12. | ALA3592702 | Binding | Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 45 mins by AlphaScreen competitive inhibition assay | Homo sapiens | 21 | ALA3588842 | single protein format | Scientific Literature | |
13. | ALA3592703 | Binding | Inhibition of interaction of beta-catenin (unknown origin) transfected in Wnt-activated HEK293 cells/Tcf4 assessed as decrease in transactivation of canonical Wnt signaling by TOPflash luciferase reporter assay | Homo sapiens | 11 | ALA3588842 | cell-based format | Scientific Literature | |
14. | ALA3592707 | Functional | Cytotoxicity against human SW480 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 12 | ALA3588842 | cell-based format | Scientific Literature | |
15. | ALA3592708 | Functional | Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 12 | ALA3588842 | cell-based format | Scientific Literature | |
16. | ALA3592709 | Functional | Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 6 | ALA3588842 | cell-based format | Scientific Literature | |
17. | ALA5105271 | Binding | Thermal stabilization of wildtype beta catenin ARD (148 to 662 residues) (unknown origin) assessed as change in melting temperature at 125 uM by DSF method | Homo sapiens | 24 | ALA5104113 | single protein format | Scientific Literature |