# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2329671 | B | Induction of RXRalpha-AD/RXRalpha-BD (unknown origin) homodimerization expressed in human HCT116 cells at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 6 | ALA2321735 | cell-based format | Scientific Literature | |
2. | ALA2329672 | B | Agonist activity at RAR (unknown origin) expressed in human HCT116 cells co-expressing RARE at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 14 | ALA2321735 | cell-based format | Scientific Literature | |
3. | ALA2329673 | B | Agonist activity at RXR (unknown origin) expressed in human HCT116 cells co-expressing RXRE at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 14 | ALA2321735 | cell-based format | Scientific Literature | |
4. | ALA2329674 | B | Agonist activity at glucocorticoid receptor (unknown origin) expressed in human HCT116 cells co-expressing GRE at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 14 | ALA2321735 | cell-based format | Scientific Literature | |
5. | ALA2329675 | B | Agonist activity at human VDR expressed in human HCT116 cells assessed as induction of recruitment of DRIP205 at 20 to 40 uM after 24 hrs by mammalian two hybrid system based luciferase reporter gene assay | Homo sapiens | 4 | ALA2321735 | cell-based format | Scientific Literature | |
6. | ALA2329676 | B | Agonist activity at human VDR expressed in human HCT116 cells assessed as induction of recruitment of SRC-1 at 20 to 40 uM after 24 hrs by mammalian two hybrid system based luciferase reporter gene assay | Homo sapiens | 4 | ALA2321735 | cell-based format | Scientific Literature | |
7. | ALA2329677 | B | Induction of VDR-RXRalpha heterodimerization in human HCT116 cells assessed as Renilla luciferase reporter gene transcriptional activity at 20 to 40 uM after 24 hrs by mammalian two-hybrid assay | Homo sapiens | 11 | ALA2321735 | cell-based format | Scientific Literature | |
8. | ALA2329678 | B | Agonist activity at human VDR expressed in human HCT116 cells assessed as CYP24A1 transcriptional activity at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 12 | ALA2321735 | cell-based format | Scientific Literature | |
9. | ALA2329679 | B | Agonist activity at human VDR expressed in human HCT116 cells co-expressing VDRE assessed as XDR3 transcriptional activity at 20 to 40 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 11 | ALA2321735 | cell-based format | Scientific Literature | |
10. | ALA2329681 | B | Agonist activity at human VDR expressed in human HCT116 cells co-expressing VDRE assessed as XDR3 transcriptional activity at 20 to 40 uM after 24 hrs by luciferase reporter gene assay relative to control in presence of resveratrol | Homo sapiens | 5 | ALA2321735 | cell-based format | Scientific Literature |