| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2329164 | F | Increase in motor activity Sabra mouse at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured on day 14 by open field test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 2. | ALA2329165 | F | Effect on FAAH gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 3. | ALA2329166 | F | Effect on CAMKK2 gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 4. | ALA2329167 | F | Effect on 5HT1A gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 5. | ALA2329168 | F | Effect on CART gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 6. | ALA2329169 | F | Effect on NPY gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 7. | ALA2329170 | F | Effect on POMC gene expression in Sabra mouse hypothalamus assessed as change in mRNA level at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 by RT-PCR analysis relative to GAPDH | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 8. | ALA2329171 | B | Displacement of [3H]resiniferatoxin from TRPV1 receptor in Wistar rat spinal cord at 10 uM relative to control | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
| 9. | ALA2329172 | B | Inhibition of rat brain FAAH using [3H]anandamide as substrate at 10 uM preincubated for 15 mins before substrate addition relative to control | Rattus norvegicus | 6 | assay format | Scientific Literature | ||
| 10. | ALA2329173 | B | Displacement of [3H]WIN-55,212-2 from human recombinant CB2 receptor expressed in CHO-K1 cells at 10 uM relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA2329174 | B | Displacement of [3H]SR141716A from human CB1 receptor expressed in rat Chem-1 cell membrane at 10 uM relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA2329175 | B | Binding affinity to human recombinant PPARalpha expressed in Escherichia coli at 10 uM for 16 hrs by spectrofluorimetric analysis relative to control | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 13. | ALA2329331 | F | Antiobesity activity in Sabra mouse assessed as change in food consumption at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured after 6 weeks relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 14. | ALA2329332 | F | Antiobesity activity in Sabra mouse assessed as change in food consumption at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured after 5 weeks relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 15. | ALA2329333 | F | Antiobesity activity in Sabra mouse assessed as change in food consumption at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured after 3 weeks relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA2329334 | F | Antiobesity activity in Sabra mouse assessed as change in food consumption at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured after 4 weeks relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 17. | ALA2329335 | F | Antiobesity activity in Sabra mouse assessed as change in body weight at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured on day 35 relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 18. | ALA2329336 | F | Antiobesity activity in Sabra mouse assessed as change in body weight at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured on day 39 relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 19. | ALA2329337 | F | Antiobesity activity in Sabra mouse assessed as change in body weight at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured on day 30 relative to control | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 20. | ALA2329338 | F | Antiobesity activity in Sabra mouse assessed as change in body weight at 1 mg/kg, ip administered on day 8, 9, 10, 11, 14, 18, 24 and 32 measured on day 25 relative to control | Mus musculus | 6 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!