# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2330264 | B | Binding affinity to GC-rich FAM-GCGCAGATTTTCTGCGC-TAMRA DNA (unknown origin) assessed as change in melting temperature at 1 uM by FRET assay | Not specified | 11 | ALA2321778 | assay format | Scientific Literature | |
2. | ALA2330265 | B | Binding affinity to AT-rich FAM-TATAAGATTTTCTTATA-TAMRA DNA (unknown origin) assessed as change in melting temperature at 1 uM by FRET assay | Not specified | 11 | ALA2321778 | assay format | Scientific Literature | |
3. | ALA2330267 | B | Selectivity ratio of deltaTm for GC-rich FAM-GCGCAGATTTTCTGCGC-TAMRA DNA (unknown origin) to deltaTm for AT-rich FAM-TATAAGATTTTCTTATA-TAMRA DNA (unknown origin) | Not specified | 11 | ALA2321778 | assay format | Scientific Literature | |
4. | ALA2330268 | F | Cytotoxicity against human A431 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
5. | ALA2330269 | F | Cytotoxicity against human A549 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
6. | ALA2330463 | T | Toxicity in ip dosed Swiss Webster mouse | Mus musculus | 2 | ALA2321778 | organism-based format | Scientific Literature | |
7. | ALA2330464 | T | Toxicity in Swiss Webster mouse assessed as weight loss at 400 ug/kg/day, ip | Mus musculus | 1 | ALA2321778 | organism-based format | Scientific Literature | |
8. | ALA2330465 | A | Cytotoxicity against human WI38 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
9. | ALA2330466 | F | Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
10. | ALA2330467 | F | Cytotoxicity against human MDA-MB-231 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
11. | ALA2330468 | F | Cytotoxicity against human MIAPaCa2 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
12. | ALA2330469 | F | Cytotoxicity against human primary CLL cells after 96 hrs by annexin V/propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
13. | ALA2330470 | F | Cytotoxicity against human A2780 cells after 96 hrs by MTT assay | Homo sapiens | 12 | ALA2321778 | cell-based format | Scientific Literature | |
14. | ALA5107837 | B | Binding affinity to AT-rich 5'-fluoro and 3'-TAMRA tagged 5'-TAT-ATA-TAG-ATA-TTT-TTT-TAT-CTA-TAT-ATA-3' hairpin DNA (unknown origin) assessed as thermal stabilization by measuring change in melting temperature at 1 uM incubated for 3 hrs by FRET analysis | Not specified | 4 | ALA5104228 | assay format | Scientific Literature | |
15. | ALA5107838 | B | Binding affinity to AT-rich 5'-fluoro and 3'-TAMRA tagged 5'-TAT-ATA-TAG-ATA-TTT-TTT-TAT-CTA-TAT-ATA-3' hairpin DNA(unknown origin) assessed as thermal stabilization by measuring change in melting temperature at 1 uM incubated for 24 hrs by FRET analysis | Not specified | 4 | ALA5104228 | assay format | Scientific Literature | |
16. | ALA5107839 | B | Binding affinity to GC-rich 5'-fluoro and 3'-TAMRA tagged 5'-TAT-AGG-GAC-AGC-CCT-ATA-3' hairpin DNA (unknown origin) assessed as thermal stabilization by measuring change in melting temperature at 1 uM incubated for 3 hrs by FRET analysis | Not specified | 4 | ALA5104228 | assay format | Scientific Literature | |
17. | ALA5107840 | B | Binding affinity to GC-rich 5'-fluoro and 3'-TAMRA tagged 5'-TAT-AGG-GAC-AGC-CCT-ATA-3' hairpin DNA (unknown origin) assessed as thermal stabilization by measuring change in melting temperature at 1 uM incubated for 24 hrs by FRET analysis | Not specified | 4 | ALA5104228 | assay format | Scientific Literature | |
18. | ALA5107841 | F | Induction of DNA damage in Caulobacter vibrioides assessed as increase in cell death upto 1 ug/ml and measured after 2 days by agar dilution method | Caulobacter vibrioides | 3 | ALA5104228 | organism-based format | Scientific Literature | |
19. | ALA5107843 | F | Induction of DNA damage in Caulobacter vibrioides assessed as accumulation of SOS-induced YFP at 1 ug/ml incubated upto 2 hrs by fluorescence microscopy | Caulobacter vibrioides | 1 | ALA5104228 | organism-based format | Scientific Literature | |
20. | ALA5107844 | F | Effect on DNA damage repair in Caulobacter vibrioides lacking recA expression assessed as decrease in cell survival rate upto 1 ug/ml and measured after 2 days by agar dilution method | Caulobacter vibrioides | 3 | ALA5104228 | organism-based format | Scientific Literature |