| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2438118 | P | Aqueous solubility of the compound in KCl at pH 7.4 at 25 degC | 10 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA2438119 | P | Partition coefficient, log P of the compound | 9 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA2438120 | B | Selectivity factor, ratio of IC50 for human placenta 17beta-HSD1 cytosolic fraction to IC50 for human placenta 17beta-HSD2 microsomal fraction | Homo sapiens | 12 | assay format | Scientific Literature | ||
| 4. | ALA2438121 | B | Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabeled, [2,4,6,7-3H]-estrone as substrate at 1 uM after 20 mins by HPLC analysis in presence of NADH relative to control | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 5. | ALA2438123 | B | Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabeled, [2,4,6,7-3H]-estradiol as substrate at 1 uM after 20 mins by HPLC analysis in presence of NAD+ relative to control | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 6. | ALA2328133 | B | Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cell using [1,2,6,7-3H]cortisol as substrate at 2 uM after 10 mins by scintillation counting analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA2328430 | B | Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cell using [1,2-3H]Cortisone as substrate at 2 uM after 10 mins by scintillation counting analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA2328431 | B | Inhibition of human recombinant 17beta-HSD5 expressed in Escherichia coli using [1,2,6,7-3H]A-dione as substrate at 1 uM by scintillation counting analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 9. | ALA2328432 | B | Inhibition of human recombinant 17beta-HSD4 SDR domain expressed in Escherichia coli using [6,7-3H]E2 as substrate at 1 uM by scintillation counting analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 10. | ALA2328440 | B | Inhibition of 17beta-HSD1 in human placental cytosolic fraction using [3H]E1 as substrate after 10 mins at 1 uM by HPLC analysis | Homo sapiens | 64 | assay format | Scientific Literature | ||
| 11. | ALA2328441 | B | Inhibition of 17beta-HSD2 in human placental microsomal fraction using [3H]E2 as substrate at 1 uM after 20 mins by HPLC analysis | Homo sapiens | 64 | microsome format | Scientific Literature |
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