# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2328568 | Binding | Inhibition of NaV1.7 ion channel (unknown origin) | Homo sapiens | 1,017 | ALA2321810 | single protein format | Scientific Literature | |
2. | ALA4040119 | ADME | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 6 | ALA4038312 | organism-based format | Scientific Literature | |
3. | ALA4040120 | ADME | Plasma clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 6 | ALA4038312 | organism-based format | Scientific Literature | |
4. | ALA4040121 | ADME | Plasma clearance in dog at 0.1 mg/kg, iv | Canis lupus familiaris | 6 | ALA4038312 | organism-based format | Scientific Literature | |
5. | ALA4040124 | ADME | Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 26 | ALA4038312 | cell-based format | Scientific Literature | |
6. | ALA4040125 | Binding | Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 27 | ALA4038312 | cell-based format | Scientific Literature | |
7. | ALA4040126 | ADME | Inhibition of human NaV1.1 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
8. | ALA4040127 | ADME | Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
9. | ALA4040128 | Binding | Inhibition of human NaV1.3 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
10. | ALA4040129 | ADME | Inhibition of human NaV1.6 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
11. | ALA4040130 | Binding | Inhibition of human NaV1.8 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
12. | ALA4040131 | Binding | Inhibition of rat NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Rattus norvegicus | 5 | ALA4038312 | cell-based format | Scientific Literature | |
13. | ALA4040132 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 26 | ALA4038312 | single protein format | Scientific Literature | |
14. | ALA4040133 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 27 | ALA4038312 | single protein format | Scientific Literature | |
15. | ALA4040134 | ADME | Apparent intrinsic clearance in human liver microsomes | Homo sapiens | 26 | ALA4038312 | assay format | Scientific Literature | |
16. | ALA4040135 | Physicochemical | Octanol-water distribution coefficient, log D of the compound at pH 7.4 by shake flask method | 17 | ALA4038312 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA4040136 | Physicochemical | Solubility of the compound at pH 6.5 | 6 | ALA4038312 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA4040137 | ADME | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 6 | ALA4038312 | assay format | Scientific Literature | |
19. | ALA4040138 | ADME | Intrinsic clearance in dog liver microsomes | Canis lupus familiaris | 6 | ALA4038312 | assay format | Scientific Literature | |
20. | ALA4040139 | ADME | Intrinsic clearance in human hepatocytes assessed per 10'6 cells | Homo sapiens | 6 | ALA4038312 | cell-based format | Scientific Literature |