# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2328568 | B | Inhibition of NaV1.7 ion channel (unknown origin) | Homo sapiens | 1,017 | ALA2321810 | single protein format | Scientific Literature | |
2. | ALA4040124 | A | Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 26 | ALA4038312 | cell-based format | Scientific Literature | |
3. | ALA4040125 | B | Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 27 | ALA4038312 | cell-based format | Scientific Literature | |
4. | ALA4040126 | A | Inhibition of human NaV1.1 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
5. | ALA4040127 | A | Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
6. | ALA4040128 | B | Inhibition of human NaV1.3 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
7. | ALA4040129 | A | Inhibition of human NaV1.6 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
8. | ALA4040130 | B | Inhibition of human NaV1.8 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Homo sapiens | 5 | ALA4038312 | cell-based format | Scientific Literature | |
9. | ALA4040131 | B | Inhibition of rat NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp method | Rattus norvegicus | 5 | ALA4038312 | cell-based format | Scientific Literature | |
10. | ALA4040132 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 26 | ALA4038312 | single protein format | Scientific Literature | |
11. | ALA4040133 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 27 | ALA4038312 | single protein format | Scientific Literature | |
12. | ALA4040134 | A | Apparent intrinsic clearance in human liver microsomes | Homo sapiens | 26 | ALA4038312 | assay format | Scientific Literature | |
13. | ALA4040145 | P | Acidic dissociation constant, pKa of the compound | 12 | ALA4038312 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA4040177 | U | Selectivity ratio of IC50 for human NaV1.1 expressed in HEK cells to IC50 for human NaV1.7 expressed in HEK cells | Homo sapiens | 2 | ALA4038312 | cell-based format | Scientific Literature | |
15. | ALA4040178 | B | Selectivity ratio of IC50 for human NaV1.3 expressed in HEK cells to IC50 for human NaV1.7 expressed in HEK cells | Homo sapiens | 2 | ALA4038312 | cell-based format | Scientific Literature | |
16. | ALA4040179 | B | Selectivity ratio of IC50 for rat NaV1.7 expressed in HEK cells to IC50 for human NaV1.7 expressed in HEK cells | 2 | ALA4038312 | cell-based format | Scientific Literature |