| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2330301 | B | Agonist activity at human MOP receptor | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA2330302 | B | Agonist activity at human KOP receptor | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA2330303 | B | Inhibition of PLD2 in human U87MG cells assessed as decrease in cell migration after 48 hrs by transwell invasion assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA2330304 | B | Inhibition of PLD1 in human U87MG cells assessed as decrease in cell migration after 48 hrs transwell invasion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2330305 | F | Increase in caspase 3/7 activation in human U87MG cells after 6 to 72 hrs under serum free conditions | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2330306 | A | Ratio of AUC in balck6 mouse brain to AUC in balck6 mouse plasma at 10 mg/kg, ip up to 6 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA2330307 | A | Cytotoxicity against human U87MG cells assessed as cell viability up to 10 uM by WST-1 assay in presence of 10% FBS relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2330308 | A | AUC in balck6 mouse plasma at 10 mg/kg, ip up to 6 hrs by LC/MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA2330309 | A | AUC in balck6 mouse lung at 10 mg/kg, ip up to 6 hrs by LC/MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA2330310 | A | AUC in balck6 mouse brain at 10 mg/kg, ip up to 6 hrs by LC/MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA2330311 | A | Fraction unbound in rat plasma after 4 hrs by equilibrium dialysis method | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
| 12. | ALA2330312 | A | Fraction unbound in human plasma after 4 hrs by equilibrium dialysis method | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 13. | ALA2330313 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA2330314 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA2330315 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA2330316 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA2330317 | A | Clearance in rat liver microsomes at 1 uM incubated for 5 mins prior to NADPH addition measured after 3 to 45 mins by LC/MS/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 18. | ALA2330318 | A | Clearance in human liver microsomes at 1 uM incubated for 5 mins prior to NADPH addition measured after 3 to 45 mins by LC/MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 19. | ALA2330319 | B | Inhibition of human ERG | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA2330320 | B | Inhibition of human MOP receptor at 10 uM by radioligand binding assay | Homo sapiens | 2 | single protein format | Scientific Literature |
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