# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2330784 | Binding | Ratio of JW74 IC50 to compound IC50 for TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay | Homo sapiens | 3 | ALA2321812 | cell-based format | Scientific Literature | |
2. | ALA2330981 | ADME | Half life in human liver microsomes | Homo sapiens | 10 | ALA2321812 | microsome format | Scientific Literature | |
3. | ALA2330982 | Binding | Inhibition of TNKS2 (unknown origin) by NAD+-dependent autopoly(ADP ribosyl)lation assay | Homo sapiens | 10 | ALA2321812 | single protein format | Scientific Literature | |
4. | ALA2330984 | Binding | Inhibition of TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay | Homo sapiens | 13 | ALA2321812 | cell-based format | Scientific Literature |