# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2330119 | B | Antagonist activity at LBD of ERalpha receptor in human HeLa cells assessed as CBP CH3 domain interaction to receptor at 100 nM after 20 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA2330121 | B | Antagonist activity at LBD of ERalpha receptor in human HeLa cells assessed as blockade of SRC-1 binding to receptor at 100 nM after 20 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA2330123 | B | Antagonist activity at ERalpha receptor in human HeLa cells assessed as inhibition of E2-induced response after 20 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2330124 | B | Agonist activity at ERalpha receptor in human HepG2 cells assessed as activation of ERalpha-based transcription at 100 nM after 20 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA2330128 | B | Agonist activity at ERalpha receptor in human MCF7 cells assessed as activation of ERalpha-based transcription at 100 nM after 20 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA2330132 | B | Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA2330133 | B | Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysis relative to 17beta-estradiol | Homo sapiens | 9 | single protein format | Scientific Literature | ||
8. | ALA2330134 | B | Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysis relative to 17beta-estradiol | Homo sapiens | 9 | single protein format | Scientific Literature | ||
9. | ALA2330135 | B | Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
10. | ALA2330136 | B | Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysis | Homo sapiens | 10 | single protein format | Scientific Literature |