| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2330137 | B | Inhibition of human factor 11a using S2366 as substrate after 10 mins by spectrophotometry | Homo sapiens | 19 | single protein format | Scientific Literature | ||
| 2. | ALA2330138 | B | Binding affinity to human factor 11a-DEGR by spectrofluorometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA2330139 | B | Inhibition of human recombinant factor 11a catalytic domain catalytic domain Lys529Ala/Arg530Ala/Arg532Ala triple mutant transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry in presence of polybrene | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2330140 | B | Inhibition of human recombinant factor 11a catalytic domain transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry in presence of polybrene | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2330141 | B | Inhibition of human wild type full length factor 11a transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry in presence of polybrene | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2330208 | B | Inhibition of human recombinant factor 11a catalytic domain Lys529Ala/Arg530Ala/Arg532Ala triple mutant transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2330209 | B | Inhibition of human recombinant factor 11a catalytic domain transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2330210 | B | Inhibition of human wild type full length factor 11a transfected in HEK293 cells using S2366 as substrate assessed as residual protease activity at 3 uM after 10 mins by spectrophotometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2330211 | B | Inhibition of human recombinant factor 11a catalytic domain Lys535Ala/Lys539Ala double mutant transfected in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2330212 | B | Ratio of IC50 for human recombinant factor 11a catalytic domain Lys529Ala/Arg530Ala/Arg532Ala triple mutant to IC50 for human recombinant factor XIa catalytic domain | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA2330213 | B | Ratio of IC50 for human recombinant factor 11a catalytic domain Arg530Ala mutant to IC50 for human recombinant factor XIa catalytic domain | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA2330214 | B | Inhibition of human recombinant factor 11a catalytic domain | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA2330215 | F | Anticoagulant activity in human plasma assessed as concentration required to double partial thromboplastin time | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 14. | ALA2330216 | F | Anticoagulant activity in human plasma assessed as concentration required to double activated partial thromboplastin time | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 15. | ALA2330217 | B | Inhibition of bovine alpha-chymotrypsin assessed as residual protease activity at 500 uM after 10 mins by spectrophotometry | Bos taurus | 3 | single protein format | Scientific Literature | ||
| 16. | ALA2330218 | B | Inhibition of bovine trypsin assessed as residual protease activity at 500 uM after 10 mins by spectrophotometry | Bos taurus | 3 | single protein format | Scientific Literature | ||
| 17. | ALA2330219 | B | Inhibition of human factor 10a assessed as residual protease activity at 500 uM after 10 mins by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA2330220 | B | Inhibition of human factor 11a using S2366 as substrate assessed as residual protease activity after 10 mins by spectrophotometry | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 19. | ALA2330221 | B | Inhibition of human thrombin assessed as residual protease activity at 500 uM after 10 mins by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature |
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