# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2340381 | B | Inhibition of L-type calcium channel (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
2. | ALA2340382 | B | Inhibition of sodium channel (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA2340383 | A | Drug uptake in Sprague-Dawley rat brain at 0.3 mg/kg, iv administered as 5 mins infusion measured after 10 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2340384 | A | Plasma concentration in Sprague-Dawley rat at 0.3 mg/kg, iv administered as 5 mins infusion measured after 10 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2340385 | A | Plasma concentration in Sprague-Dawley rat at 0.3 mg/kg, iv administered as 5 mins infusion measured at 5 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2340386 | F | Antiarrhythmic activity in Sprague-Dawley rat assessed as decrease in ventricular effective refractory period at 0.3 mg/kg, iv administered as 5 mins infusion measured after 5 mins relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2340387 | F | Antiarrhythmic activity in Sprague-Dawley rat assessed as decrease in QT interval at 0.3 mg/kg, iv administered as 5 mins infusion measured after 5 mins relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2340388 | F | Antiarrhythmic activity in Sprague-Dawley rat assessed as increase in heart rate at 0.3 mg/kg, iv administered as 5 mins infusion measured after 5 mins relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2340389 | F | Antiarrhythmic activity in Sprague-Dawley rat assessed as decrease in blood pressure at 0.3 mg/kg, iv administered as 5 mins infusion measured after 5 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2340390 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
11. | ALA2340391 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
12. | ALA2340392 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA2340393 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA2340394 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA2340395 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA2340396 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA2340397 | B | Transactivation of PXR (unknown origin) | Homo sapiens | 13 | single protein format | Scientific Literature | ||
18. | ALA2340399 | B | Inhibition of human ERG current in HEK293 cells at 10 uM by patch clamp method relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
19. | ALA2340853 | B | Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp assay | Homo sapiens | 34 | cell-based format | Scientific Literature |