| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2341161 | P | Aqueous solubility in potassium phosphate buffer at pH 5.5 after 24 hrs by HPLC analysis | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA2341162 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 3. | ALA2341163 | A | Cmax in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 4. | ALA2341164 | A | AUC in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 5. | ALA2341165 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 6. | ALA2341166 | A | Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 7. | ALA2341167 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 8. | ALA2341168 | A | Inhibition of CYP3A4 (unknown origin)-mediated midazolam hydroxylation to 1'-Hydroxymidazolam | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA2341169 | A | Inhibition of CYP2D6 (unknown origin)-mediated bufuralol hydroxylation to 4'-Hydroxybufuralol | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 10. | ALA2341170 | A | Inhibition of CYP2C9 (unknown origin)-mediated tolbutamide hydroxylation to hydroxy tolbutamide | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA2341171 | A | Inhibition of CYP1A2 (unknown origin)-mediated phenaceten demethylation to acetaminophen | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA2341172 | A | Inhibition of CYP3A4 (unknown origin)-mediated midazolam hydroxylation to 1'-Hydroxymidazolam at 10 uM relative to control | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 13. | ALA2341173 | A | Inhibition of CYP2D6 (unknown origin)-mediated bufuralol hydroxylation to 4'-Hydroxybufuralol at 10 uM relative to control | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 14. | ALA2341174 | A | Inhibition of CYP2C9 (unknown origin)-mediated tolbutamide hydroxylation to hydroxy tolbutamide at 10 uM relative to control | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 15. | ALA2341175 | A | Inhibition of CYP1A2 (unknown origin)-mediated phenaceten demethylation to acetaminophen at 10 uM relative to control | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 16. | ALA2341176 | B | Inhibition of ROCK1 (unknown origin) after 4 hrs by HTRF assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 17. | ALA2341177 | B | Inhibition of p38 (unknown origin) using biotinylated Flag-ATF2 as substrate after 30 mins by HTRF assay | Homo sapiens | 12 | protein format | Scientific Literature | ||
| 18. | ALA2341178 | B | Inhibition of JNK3 alpha1 (unknown origin) using biotinylated Flag-ATF2 as substrate after 15 mins by HTRF assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 19. | ALA2341179 | B | Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATP | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 20. | ALA2341180 | B | Inhibition of PKA (unknown origin) after 70 mins by luminescence assay | Homo sapiens | 44 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!