# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2345551 | F | Cytotoxicity against mouse L5178Y cells assessed as inhibition of cell proliferation by MTT assay | Mus musculus | 6 | ALA2331160 | cell-based format | Scientific Literature | |
2. | ALA2344160 | B | Inhibition of ERBB2 (unknown origin) | Homo sapiens | 5 | ALA2331160 | single protein format | Scientific Literature | |
3. | ALA2344161 | B | Inhibition of EGFR (unknown origin) | Homo sapiens | 5 | ALA2331160 | single protein format | Scientific Literature | |
4. | ALA2344163 | B | Inhibition of CDK4/cyclin-D1 (unknown origin) | Homo sapiens | 5 | ALA2331160 | protein complex format | Scientific Literature | |
5. | ALA2344167 | B | Inhibition of aurora-B (unknown origin) | Homo sapiens | 5 | ALA2331160 | single protein format | Scientific Literature | |
6. | ALA2344168 | B | Inhibition of aurora-A (unknown origin) | Homo sapiens | 5 | ALA2331160 | single protein format | Scientific Literature | |
7. | ALA3637317 | B | Inhibition of ACAT in human MDM cells assessed as inhibition of foam cell formation by measuring acetylated LDL-induced [3H]cholesterol ester accumulation at 5 uM after 24 hrs in presence of 0.1 mM [3H]oleate | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
8. | ALA3637318 | A | Cytotoxicity against human MDM cells at 5 uM after 24 hrs | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
9. | ALA3637319 | B | Inhibition of human ACAT1 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
10. | ALA3637434 | B | Inhibition of human ACAT2 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
11. | ALA3637435 | A | Cytotoxicity against CHO cells at 5 uM | Cricetulus griseus | 2 | ALA3632472 | cell-based format | Scientific Literature | |
12. | ALA3637442 | F | Effect on triacylglycerol accumulation in human MDM cells at 5 uM after 24 hrs in presence of 50 ug/ml acetylated LDL and 0.1 mM [3H]oleate | Homo sapiens | 2 | ALA3632472 | cell-based format | Scientific Literature | |
13. | ALA3637443 | F | Effect on phospholipid accumulation in human MDM cells at 5 uM after 24 hrs in presence of 50 ug/ml acetylated LDL and 0.1 mM [3H]oleate | Homo sapiens | 2 | ALA3632472 | cell-based format | Scientific Literature | |
14. | ALA3637444 | B | Inhibition of human ACAT1 expressed in CHO cells at 5 uM using [14C]oleoyl-CoA as substrate | Homo sapiens | 4 | ALA3632472 | cell-based format | Scientific Literature | |
15. | ALA3637445 | B | Inhibition of human ACAT2 expressed in CHO cells at 5 uM using [14C]oleoyl-CoA as substrate | Homo sapiens | 4 | ALA3632472 | cell-based format | Scientific Literature |