# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2342501 | P | Kinetic solubility of the compound | 3 | ALA2331117 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA2342502 | A | Apparent permeability across MDCK cells | Canis lupus familiaris | 5 | ALA2331117 | cell-based format | Scientific Literature | |
3. | ALA2342503 | A | Metabolic stability in mouse liver microsomes after 30 mins | Mus musculus | 28 | ALA2331117 | microsome format | Scientific Literature | |
4. | ALA2342506 | B | Selectivity ratio of IC50 for PI3Kalpha (unknown origin) to IC50 for mTOR (unknown origin) | Homo sapiens | 4 | ALA2331117 | assay format | Scientific Literature | |
5. | ALA2342507 | B | Inhibition of mTORC1-mediated phosphorylation of S6 at serine 240/244 in human PC3 cells after 3 hrs by ELISA | Homo sapiens | 28 | ALA2331117 | cell-based format | Scientific Literature | |
6. | ALA2342508 | B | Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assay | Homo sapiens | 31 | ALA2331117 | single protein format | Scientific Literature | |
7. | ALA2342509 | B | Inhibition of mTORC1 (unknown origin)-mediated 4EBP1 phosphorylation after 120 mins by ELISA | Homo sapiens | 31 | ALA2331117 | assay format | Scientific Literature | |
8. | ALA5245700 | B | Inhibition of mTOR (unknown origin) | Homo sapiens | 19 | ALA5244238 | single protein format | Scientific Literature | |
9. | ALA5245707 | F | Selectivity index, ratio of IC50 for PI3Kalpha (unknown origin) to IC50 for mTOR (unknown origin) | Homo sapiens | 2 | ALA5244238 | assay format | Scientific Literature | |
10. | ALA5245712 | B | Inhibition of PI3Kalpha (unknown origin) | Homo sapiens | 2 | ALA5244238 | single protein format | Scientific Literature |