| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2346170 | B | Ratio of IC50 for His-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE3) to IC50 for recombinant AKR1C3 (unknown origin) overexpressed in human HCT116 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA2346173 | B | Inhibition of recombinant AKR1C3 (unknown origin) overexpressed in human HCT116 cells assessed as inhibition of aerobic reduction of dinitrobenzamide PR-104A to its hydroxylamine metabolite by LC-MS/MS assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA2346174 | B | Inhibition of His-tagged human AKR1C4 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of reduction of non-fluorescent ketone probe to fluorescent alcohol after 1 hr by competitive fluorescence assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 4. | ALA2346175 | B | Inhibition of His-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of reduction of non-fluorescent ketone probe to fluorescent alcohol after 1 hr by competitive fluorescence assay | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 5. | ALA2346176 | B | Inhibition of His-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of reduction of non-fluorescent ketone probe to fluorescent alcohol after 1 hr by competitive fluorescence assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 6. | ALA2346177 | B | Inhibition of His-tagged human AKR1C1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of reduction of non-fluorescent ketone probe to fluorescent alcohol after 1 hr by competitive fluorescence assay | Homo sapiens | 14 | assay format | Scientific Literature |
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