# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3075343 | B | Inhibition of Rattus norvegicus (rat) lens aldose reductase | Rattus norvegicus | 38 | ALA3046187 | single protein format | Scientific Literature | |
2. | ALA2339983 | A | Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability after 24 hrs by MTT assay | Homo sapiens | 14 | ALA2331345 | cell-based format | Scientific Literature | |
3. | ALA2339984 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition at 250 ug/ml measured every 24 hrs by BACTEC radiosusceptibility assay | Mycobacterium tuberculosis | 6 | ALA2331345 | organism-based format | Scientific Literature | |
4. | ALA4340227 | F | Antiproliferative activity against human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in cell viability at 2.5 uM incubated for 36 hrs by MTS assay | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature | |
5. | ALA4340228 | B | Inhibition of NOTCH1 signalling in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in N1Val protein expression at 2.5 uM incubated for 36 hrs by Western blot analysis | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature | |
6. | ALA4340229 | B | Inhibition of NOTCH1 signalling in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in DELTEX1 mRNA expression at 2.5 uM incubated for 36 hrs by RT-PCR analysis | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature | |
7. | ALA4340230 | F | Antiproliferative activity against human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in cell viability incubated for 36 hrs by MTS assay | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature |