# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2339116 | F | Cytotoxicity against human DU145 cells expressing AGT after 4 to 24 hrs by clonogenic assay in presence of 100 uM of AGT inhibitor O6-BG | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA2339117 | F | Induction of AGT ablation in human DU145 cells assessed as [benzene-3H]-O6-benzylguanine binding at 80 uM after 4 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA2339118 | F | Induction of AGT ablation in human DU145 cells assessed as [benzene-3H]-O6-benzylguanine binding at 80 uM after 2 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2339119 | B | Binding affinity to mouse L1210 cell DNA assessed as DNA cross-linking activity at 10 to 50 uM using H33258 dye by rapid DNA renaturation assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
5. | ALA2339120 | F | Cytotoxicity against human DU145 cells expressing AGT at 10 to 80 uM after 4 hrs by clonogenic assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA2339121 | P | Half life in 1 mM potassium phosphate buffer at pH 7.4 at 50 uM by spectrophotometric analysis | 4 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA2339122 | F | Ratio of laromustine IC50 for compound IC50 for human DU145 cells expressing AGT | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA2339123 | F | Cytotoxicity against human DU145 cells expressing AGT after 4 to 24 hrs by clonogenic assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA2339124 | F | Ratio of laromustine IC50 for compound IC50 for mouse AGT negative EMT6 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA2339125 | F | Cytotoxicity against mouse AGT negative EMT6 cells under aerobic conditions after 4 to 24 hrs by clonogenic assay | Mus musculus | 3 | cell-based format | Scientific Literature |