# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2343820 | A | Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylation | Homo sapiens | 20 | microsome format | Scientific Literature | ||
2. | ALA2343821 | P | Kinetic solubility of the compound at pH 6.5 phosphate buffer by nephelometric analysis | 20 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA2343822 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma cruzi Tulahuen TcVI extracellular trypomastigotes forms | 54 | cell-based format | Scientific Literature | |||
4. | ALA2343823 | A | Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay | Rattus norvegicus | 56 | cell-based format | Scientific Literature | ||
5. | ALA2343824 | F | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen TcVI extracellular trypomastigotes forms transfected with beta-galactosidase gene infected in rat L6 cells assessed as inhibition of parasite growth after 4 days | Trypanosoma cruzi | 56 | organism-based format | Scientific Literature |